Assay Detail
Functional
CHEMBL3584296
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Antiviral activity against Sindbis virus strain HRsp infected in african green monkey Vero cells assessed as inhibition of virus induced cell death measured after 7 days
16
Total Activities
16
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Sindbis virus |
| Cell Type | Vero |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Antiviral Activity of Flexibilane and Tigliane Diterpenoids from Stillingia lineata.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 16 | 4.75 | 5.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3582006 | — | — | 1 | 5.30 |
| CHEMBL3582007 | — | — | 1 | 4.96 |
| CHEMBL76 | CHLOROQUINE | 4.0 | 1 | 4.96 |
| CHEMBL3581999 | — | — | 1 | 4.39 |
| CHEMBL3581995 | — | — | 1 | 4.16 |
| CHEMBL3581994 | — | — | 1 | - |
| CHEMBL3581996 | — | — | 1 | - |
| CHEMBL3581997 | — | — | 1 | - |
| CHEMBL3581998 | — | — | 1 | - |
| CHEMBL3582000 | — | — | 1 | - |
| CHEMBL3582001 | — | — | 1 | - |
| CHEMBL3582002 | — | — | 1 | - |
| CHEMBL3582003 | — | — | 1 | - |
| CHEMBL3582004 | — | — | 1 | - |
| CHEMBL3582005 | — | — | 1 | - |
| CHEMBL518887 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3582006 | — | EC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL3582007 | — | EC50 | = | 11000.0 | nM | 4.96 |
| CHEMBL76 | CHLOROQUINE | EC50 | = | 11000.0 | nM | 4.96 |
| CHEMBL3581999 | — | EC50 | = | 41000.0 | nM | 4.39 |
| CHEMBL3581995 | — | EC50 | = | 70000.0 | nM | 4.16 |
| CHEMBL3581994 | — | EC50 | - | — | - | |
| CHEMBL3581996 | — | EC50 | = | 109000.0 | nM | - |
| CHEMBL3581997 | — | EC50 | - | — | - | |
| CHEMBL3581998 | — | EC50 | - | — | - | |
| CHEMBL3582000 | — | EC50 | - | — | - | |
| CHEMBL3582001 | — | EC50 | - | — | - | |
| CHEMBL3582002 | — | EC50 | - | — | - | |
| CHEMBL3582003 | — | EC50 | - | — | - | |
| CHEMBL3582004 | — | EC50 | - | — | - | |
| CHEMBL3582005 | — | EC50 | > | 255000.0 | nM | - |
| CHEMBL518887 | — | EC50 | > | 289000.0 | nM | - |