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Compound Detail

CHEMBL3582007

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CCCCCCCCC(=O)/C=C/C=C/C=C/C(=O)O[C@@]12C[C@@H](C)[C@@]3(O)[C@@H](C=C(CO)C[C@]4(O)C(=O)C(C)=C[C@@H]34)[C@@H]1C2(C)C

Basic Information

ChEMBL ID CHEMBL3582007
Phase Preclinical
Structure Type MOL
InChI Key VRNFFDMZKHRMEH-KNMGUQBGSA-N
4
Targets
4
Activities
1
Assay Types
0
PK Parameters
11
Publications
0
Known Names

Molecular Properties

594.8
MW (Da)
5.50
ALogP
7
HBA
3
HBD
121.1
PSA (Ų)
0.08
QED
2
Ro5 Violations
13
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C36H50O7
MW 594.79
Aromatic Rings 0
Heavy Atoms 43
NP-Likeness 2.53

Activity Summary

EC50 4 meas. best 7.75

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Human immunodeficiency virus 2
CHEMBL380
EC50 7.75 7.75 18.0 1
Human immunodeficiency virus 1
CHEMBL378
EC50 7.37 7.37 43.0 1
NON-PROTEIN TARGET
CHEMBL3879801
EC50 5.66 5.66 2200.0 1
Sindbis virus
CHEMBL613725
EC50 4.96 4.96 11000.0 1

Activity Data Samples

Top measurements by pChEMBL value

Literature References

Data from ChEMBL 36 via Core Engine