Assay Detail
Functional
CHEMBL5520190
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Cytostatic activity against mouse B16-F10 cells after 24 hrs by CCK-8 assay
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | B16-F10 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Three Rounds of Stability-Guided Optimization and Systematical Evaluation of Oncolytic Peptide LTX-315.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 4.04 | 4.04 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5555594 | — | — | 1 | 4.04 |
| CHEMBL4297628 | RUXOTEMITIDE | 2.0 | 1 | - |
| CHEMBL5555708 | — | — | 1 | - |
| CHEMBL5564867 | — | — | 1 | - |
| CHEMBL5561453 | — | — | 1 | - |
| CHEMBL5566008 | — | — | 1 | - |
| CHEMBL5549764 | — | — | 1 | - |
| CHEMBL5559375 | — | — | 1 | - |
| CHEMBL5561051 | — | — | 1 | - |
| CHEMBL5556048 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5555594 | — | IC50 | = | 92300.0 | nM | 4.04 |
| CHEMBL4297628 | RUXOTEMITIDE | IC50 | = | 108800.0 | nM | - |
| CHEMBL5555708 | — | IC50 | = | 112100.0 | nM | - |
| CHEMBL5564867 | — | IC50 | > | 300000.0 | nM | - |
| CHEMBL5561453 | — | IC50 | = | 234300.0 | nM | - |
| CHEMBL5566008 | — | IC50 | > | 300000.0 | nM | - |
| CHEMBL5549764 | — | IC50 | > | 300000.0 | nM | - |
| CHEMBL5559375 | — | IC50 | = | 169500.0 | nM | - |
| CHEMBL5561051 | — | IC50 | = | 250600.0 | nM | - |
| CHEMBL5556048 | — | IC50 | = | 170300.0 | nM | - |