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Compound Detail

CHEMBL5555594

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NCCCCCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(N)=O)C(c1ccccc1)c1ccccc1

Basic Information

ChEMBL ID CHEMBL5555594
Phase Preclinical
Structure Type MOL
InChI Key BAVKMWLZVZIMAR-CEGAYZSVSA-N
8
Targets
9
Activities
1
Assay Types
0
PK Parameters
10
Publications
0
Known Names

Molecular Properties

1553.0
MW (Da)

Drug Information

Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C84H117N19O10
MW 1552.98

Activity Summary

IC50 9 meas. best 5.19

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
A20
CHEMBL613850
IC50 5.19 5.19 6400.0 1
U-937
CHEMBL612794
IC50 5.17 5.17 6700.0 1
Unchecked
CHEMBL612545
IC50 4.88 4.88 13300.0 1
ES-2
CHEMBL5058622
IC50 4.61 4.61 24400.0 1
NCI/ADR-RES
CHEMBL613829
IC50 4.36 4.36 43800.0 1
HeLa
CHEMBL399
IC50 4.32 4.32 47700.0 1
B16-F10
CHEMBL612656
IC50 4.04 4.04 92300.0 1
MRC5
CHEMBL614181
IC50 4.0 4.0 98900.0 1

Activity Data Samples

Top measurements by pChEMBL value

Literature References

Data from ChEMBL 36 via Core Engine