Compound Detail
CHEMBL1341399
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Basic Information
| ChEMBL ID | CHEMBL1341399 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | HOFXWHWZEHOWPR-SNAWJCMRSA-N |
3
Targets
7
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
297.1
MW (Da)
3.33
ALogP
4
HBA
1
HBD
55.1
PSA (Ų)
0.70
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 7 meas. best 5.32
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Large ribosomal subunit protein eL19A CHEMBL1741172 | EC50 | 5.32 | 5.32 | 4837.0 | 1 |
| BJ CHEMBL614358 | EC50 | 5.29 | 5.22 | 5075.0 | 3 |
| Unchecked CHEMBL612545 | EC50 | 5.16 | 4.97 | 6877.0 | 3 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Large ribosomal subunit protein eL19A | EC50 | = | 4837.0 | nM | 5.32 | PUBCHEM_BIOASSAY: Dose Response of TOR pathway GFP-fusion proteins in Saccharomy... | - |
| BJ | EC50 | = | 5075.0 | nM | 5.29 | PUBCHEM_BIOASSAY: Luminescence Cell-Based Dose Confirmation HTS to Identify Comp... | - |
| BJ | EC50 | = | 5752.0 | nM | 5.24 | PUBCHEM_BIOASSAY: Luminescence Cell-Based Dose Response HTS to Identify Compound... | - |
| Unchecked | EC50 | = | 6877.0 | nM | 5.16 | PUBCHEM_BIOASSAY: Luminescence Cell-Based Dose Response HTS to Identify Compound... | - |
| BJ | EC50 | = | 7374.0 | nM | 5.13 | PUBCHEM_BIOASSAY: Luminescence Cell-Based Dose Response HTS to Identify Compound... | - |
| Unchecked | EC50 | = | 13100.0 | nM | 4.88 | PUBCHEM_BIOASSAY: Dose response counterscreen for uHTS small molecule activators... | - |
| Unchecked | EC50 | = | 13400.0 | nM | 4.87 | PUBCHEM_BIOASSAY: Dose response confirmation of small molecule activators of the... | - |
Data from ChEMBL 36 via Core Engine