Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL1367034

Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
COc1cc2c(c(OC)c1OC)-c1ccc(OC)c(=O)cc1[C@@H](N(C)CC#CCO)CC2

Basic Information

ChEMBL ID CHEMBL1367034
Phase Preclinical
Structure Type MOL
InChI Key GCPWRAPSDFLJDR-IBGZPJMESA-N
2
Targets
6
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

439.5
MW (Da)
2.66
ALogP
7
HBA
1
HBD
77.5
PSA (Ų)
0.69
QED
0
Ro5 Violations
6
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C25H29NO6
MW 439.51
Aromatic Rings 2
Heavy Atoms 32
NP-Likeness 0.67

Activity Summary

EC50 4 meas. best 6.21
IC50 2 meas. best 6.64

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Unchecked
CHEMBL612545
IC50 6.64 6.445 226.3 2
BJ
CHEMBL614358
EC50 6.21 5.33 616.0 3
Unchecked
CHEMBL612545
EC50 5.84 5.84 1449.0 1

Activity Data Samples

Top measurements by pChEMBL value

Data from ChEMBL 36 via Core Engine