Compound Detail
CHEMBL1367268
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Basic Information
| ChEMBL ID | CHEMBL1367268 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UBRFTWYVMMELCZ-UHFFFAOYSA-N |
4
Targets
4
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
328.4
MW (Da)
3.31
ALogP
6
HBA
0
HBD
61.2
PSA (Ų)
0.55
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 3 meas. best 5.39
IC50 1 meas. best 6.71
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 6.71 | 6.71 | 195.0 | 1 |
| Streptokinase A CHEMBL1293228 | EC50 | 5.39 | 5.39 | 4082.0 | 1 |
| Streptococcus sp. 'group A' CHEMBL612389 | EC50 | 4.93 | 4.93 | 11846.0 | 1 |
| Streptococcus CHEMBL612313 | EC50 | 4.54 | 4.54 | 28786.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 195.0 | nM | 6.71 | PUBCHEM_BIOASSAY: High Throughput Screen to Identify Inhibitors of Mycobacterium... | - |
| Streptokinase A | EC50 | = | 4082.0 | nM | 5.39 | PUBCHEM_BIOASSAY: Luminescence Microorganism-Based Dose Confirmation HTS to Iden... | - |
| Streptococcus sp. 'group A' | EC50 | = | 11846.0 | nM | 4.93 | PUBCHEM_BIOASSAY: Luminescence Microorganism-Based Dose Confirmation HTS to Iden... | - |
| Streptococcus | EC50 | = | 28786.0 | nM | 4.54 | PUBCHEM_BIOASSAY: Luminescence Microorganism-Based Dose Response HTS to Identify... | - |
Data from ChEMBL 36 via Core Engine