Compound Detail
CHEMBL1518149
INDOCATE 🧪 Phase II
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🧪 Phase II
Basic Information
| ChEMBL ID | CHEMBL1518149 |
| Name | INDOCATE |
| Phase | Phase II |
| Structure Type | MOL |
| InChI Key | YKWQHMLRAPIWDP-UHFFFAOYSA-N |
1
Targets
8
Activities
1
Assay Types
0
PK Parameters
0
Publications
2
Known Names
Molecular Properties
350.5
MW (Da)
4.02
ALogP
4
HBA
0
HBD
34.5
PSA (Ų)
0.63
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Chirality | Achiral |
Activity Summary
IC50 8 meas. best 5.42
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 5.42 | 5.0325 | 3844.6 | 8 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 3844.58 | nM | 5.42 | PubChem BioAssay. insulin secretion from INS-1E cells in the presence of 5 mM gl... | - |
| Unchecked | IC50 | = | 5474.0 | nM | 5.26 | PubChem BioAssay. GSK3B-pretreated HCT116 viability from Cell TiterGlo-IC50. (... | - |
| Unchecked | IC50 | = | 8778.6 | nM | 5.06 | PubChem BioAssay. SW480 viability from Cell TiterGlo-IC50. (Class of assay: co... | - |
| Unchecked | IC50 | = | 11272.1 | nM | 4.95 | PubChem BioAssay. DLD-1 viability from Cell TiterGlo-IC50. (Class of assay: co... | - |
| Unchecked | IC50 | = | 11761.1 | nM | 4.93 | PubChem BioAssay. HCT116 viability from Cell TiterGlo-IC50. (Class of assay: c... | - |
| Unchecked | IC50 | = | 11964.5 | nM | 4.92 | PubChem BioAssay. SNU-C1 viability from Cell TiterGlo-IC50. (Class of assay: c... | - |
| Unchecked | IC50 | = | 12769.4 | nM | 4.89 | PubChem BioAssay. RKO viability from Cell TiterGlo-IC50. (Class of assay: conf... | - |
| Unchecked | IC50 | = | 14913.88 | nM | 4.83 | PubChem BioAssay. insulin secretion from INS-1E cells in the presence of 0.1 mM ... | - |
Data from ChEMBL 36 via Core Engine