Compound Detail
CHEMBL1975208
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Basic Information
| ChEMBL ID | CHEMBL1975208 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | BZBXKKJGOVUTDG-UHFFFAOYSA-N |
4
Targets
6
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
348.3
MW (Da)
0.78
ALogP
5
HBA
3
HBD
115.4
PSA (Ų)
0.76
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 6 meas. best 6.6
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Casein kinase I isoform gamma-1 CHEMBL2426 | Ki | 6.6 | 6.3 | 251.2 | 2 |
| SRSF protein kinase 1 CHEMBL4375 | Ki | 5.4 | 5.4 | 3981.1 | 1 |
| Serine/threonine-protein kinase pim-3 CHEMBL5407 | Ki | 5.3 | 5.25 | 5011.9 | 2 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 3 CHEMBL4575 | Ki | 5.2 | 5.2 | 6309.6 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Casein kinase I isoform gamma-1 | Ki | = | 251.19 | nM | 6.6 | PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member na... | - |
| Casein kinase I isoform gamma-1 | Ki | = | 1000.0 | nM | 6.0 | PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member na... | - |
| SRSF protein kinase 1 | Ki | = | 3981.07 | nM | 5.4 | PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member na... | - |
| Serine/threonine-protein kinase pim-3 | Ki | = | 5011.87 | nM | 5.3 | PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member na... | - |
| Serine/threonine-protein kinase pim-3 | Ki | = | 6309.57 | nM | 5.2 | PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member na... | - |
| Dual specificity tyrosine-phosphorylation-regulated kinase 3 | Ki | = | 6309.57 | nM | 5.2 | PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member na... | - |
Data from ChEMBL 36 via Core Engine