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Compound Detail

CHEMBL3198213

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N=C(N)NNc1ccc(N=NC(N)=S)cc1

Basic Information

ChEMBL ID CHEMBL3198213
Phase Preclinical
Structure Type MOL
InChI Key ANZIOUQAFBXNHU-UHFFFAOYSA-N
4
Targets
6
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

237.3
MW (Da)
0.82
ALogP
4
HBA
5
HBD
124.7
PSA (Ų)
0.17
QED
0
Ro5 Violations
3
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C8H11N7S
MW 237.29
Aromatic Rings 1
Heavy Atoms 16
NP-Likeness -1.16

Activity Summary

EC50 3 meas. best 6.46
IC50 3 meas. best 5.16

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Streptococcus
CHEMBL612313
EC50 6.46 6.46 350.0 1
Unchecked
CHEMBL612545
IC50 5.16 4.8833 6850.0 3
Zinc finger protein mex-5
CHEMBL1293319
EC50 5.01 5.01 9727.0 1
RNA-binding protein pos-1
CHEMBL1293304
EC50 4.12 4.12 76496.0 1

Activity Data Samples

Top measurements by pChEMBL value

Data from ChEMBL 36 via Core Engine