Compound Detail
CHEMBL32174
N-(3-HYDROXYPROPYL)PALMITAMIDE Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL32174 |
| Name | N-(3-HYDROXYPROPYL)PALMITAMIDE |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | XFKOWTJQIZCEEL-UHFFFAOYSA-N |
2
Targets
4
Activities
1
Assay Types
0
PK Parameters
5
Publications
0
Known Names
Molecular Properties
313.5
MW (Da)
4.97
ALogP
2
HBA
2
HBD
49.3
PSA (Ų)
0.37
QED
0
Ro5 Violations
17
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 4 meas. best 5.42
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Fatty-acid amide hydrolase 1 CHEMBL2243 | IC50 | 5.42 | 5.42 | 3801.9 | 1 |
| Rattus norvegicus CHEMBL376 | IC50 | 5.42 | 5.1967 | 3801.9 | 3 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Rattus norvegicus | IC50 | = | 3801.89 | nM | 5.42 | Inhibition of [3H]- AEA metabolism (N-arachidonoylethanolamine) in rat brain hom... | 12672243 |
| Fatty-acid amide hydrolase 1 | IC50 | = | 3801.89 | nM | 5.42 | Inhibition of FAAH | 18983142 |
| Rattus norvegicus | IC50 | = | 6918.31 | nM | 5.16 | Inhibition of [3H]- AEA metabolism (N-arachidonoylethanolamine) using rat brain ... | 12672243 |
| Rattus norvegicus | IC50 | = | 9772.37 | nM | 5.01 | Inhibition of [3H]- AEA metabolism (N-arachidonoylethanolamine) using rat brain ... | 12672243 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1007/s00044-010-9357-7 | Mus musculus | 13 |
| 12672243 | 10.1021/jm0209679 | Rattus norvegicus | 6 |
| 12672243 | 10.1021/jm0209679 | Cannabinoid receptor 1 | 1 |
| 12672243 | 10.1021/jm0209679 | Cannabinoid receptor 2 | 1 |
| 18983142 | 10.1021/jm800311k | Fatty-acid amide hydrolase 1 | 1 |
Data from ChEMBL 36 via Core Engine