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Compound Detail

CHEMBL3896444

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CC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O)C(C)C)C(C)C

Basic Information

ChEMBL ID CHEMBL3896444
Phase Preclinical
Structure Type BOTH
InChI Key QODBBYHKZNVXSP-VNQVEJEMSA-N
2
Targets
10
Activities
3
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

3203.9
MW (Da)

Drug Information

Molecule Type Protein
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C152H244N42O34
MW 3203.88

Activity Summary

EC50 6 meas. best 5.64
IC50 3 meas. best 7.19
Kd 1 meas. best 7.21

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Unchecked
CHEMBL612545
Kd 7.21 7.21 61.8 1
Tissue factor pathway inhibitor
CHEMBL3713062
IC50 7.19 7.19 65.0 3
Tissue factor pathway inhibitor
CHEMBL3713062
EC50 5.64 5.605 2290.0 6

Activity Data Samples

Top measurements by pChEMBL value

Data from ChEMBL 36 via Core Engine