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Assay Detail

CHEMBL1963738

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: CAMK2D
ChEMBL ↗
640
Total Activities
626
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Category other
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Calcium/calmodulin-dependent protein kinase type II subunit delta (CHEMBL2801) ↗
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

PubChem BioAssay data set

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 640 5.91 8.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL509032 TAE-684 — 1 8.40
CHEMBL1998159 — — 1 8.30
CHEMBL2002726 — — 1 8.00
CHEMBL1991063 — — 1 7.90
CHEMBL1970903 — — 1 7.80
CHEMBL2001751 — — 1 7.80
CHEMBL1993661 — — 1 7.70
CHEMBL1990885 — — 1 7.60
CHEMBL1965836 — — 1 7.60
CHEMBL1994669 — — 1 7.50
CHEMBL565612 SOTRASTAURIN 2.0 1 7.50
CHEMBL1995813 — — 1 7.40
CHEMBL1996817 — — 1 7.40
CHEMBL1986943 — — 2 7.20
CHEMBL1982957 — — 1 7.20
CHEMBL1992922 — — 1 7.10
CHEMBL1969588 — — 1 7.10
CHEMBL1982711 — — 1 7.10
CHEMBL1973540 — — 1 7.10
CHEMBL1984548 — — 1 7.00
CHEMBL1987034 — — 1 6.90
CHEMBL398951 — — 1 6.90
CHEMBL1967878 CENISERTIB 2.0 1 6.90
CHEMBL2005509 — — 1 6.90
CHEMBL1968380 — — 1 6.80
CHEMBL592030 — — 1 6.80
CHEMBL2000071 — — 1 6.80
CHEMBL1967887 — — 1 6.80
CHEMBL1992220 — — 1 6.80
CHEMBL1988163 — — 1 6.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL509032 TAE-684 Ki = 3.981 nM 8.40
CHEMBL1998159 — Ki = 5.012 nM 8.30
CHEMBL2002726 — Ki = 10.0 nM 8.00
CHEMBL1991063 — Ki = 12.59 nM 7.90
CHEMBL2001751 — Ki = 15.85 nM 7.80
CHEMBL1970903 — Ki = 15.85 nM 7.80
CHEMBL1993661 — Ki = 19.95 nM 7.70
CHEMBL1990885 — Ki = 25.12 nM 7.60
CHEMBL1965836 — Ki = 25.12 nM 7.60
CHEMBL565612 SOTRASTAURIN Ki = 31.62 nM 7.50
CHEMBL1994669 — Ki = 31.62 nM 7.50
CHEMBL1995813 — Ki = 39.81 nM 7.40
CHEMBL1996817 — Ki = 39.81 nM 7.40
CHEMBL1986943 — Ki = 63.1 nM 7.20
CHEMBL1982957 — Ki = 63.1 nM 7.20
CHEMBL1986943 — Ki = 63.1 nM 7.20
CHEMBL1973540 — Ki = 79.43 nM 7.10
CHEMBL1969588 — Ki = 79.43 nM 7.10
CHEMBL1982711 — Ki = 79.43 nM 7.10
CHEMBL1992922 — Ki = 79.43 nM 7.10
CHEMBL1984548 — Ki = 100.0 nM 7.00
CHEMBL1987034 — Ki = 125.89 nM 6.90
CHEMBL1967878 CENISERTIB Ki = 125.89 nM 6.90
CHEMBL398951 — Ki = 125.89 nM 6.90
CHEMBL2005509 — Ki = 125.89 nM 6.90
CHEMBL1992220 — Ki = 158.49 nM 6.80
CHEMBL2000071 — Ki = 158.49 nM 6.80
CHEMBL592030 — Ki = 158.49 nM 6.80
CHEMBL1967887 — Ki = 158.49 nM 6.80
CHEMBL1968380 — Ki = 158.49 nM 6.80
CHEMBL1988537 — Ki = 199.53 nM 6.70
CHEMBL1983111 — Ki = 199.53 nM 6.70
CHEMBL1965507 — Ki = 199.53 nM 6.70
CHEMBL1969537 — Ki = 199.53 nM 6.70
CHEMBL1988163 — Ki = 199.53 nM 6.70
CHEMBL1973720 — Ki = 251.19 nM 6.60
CHEMBL244378 — Ki = 251.19 nM 6.60
CHEMBL1973720 — Ki = 251.19 nM 6.60
CHEMBL1972339 — Ki = 251.19 nM 6.60
CHEMBL1998432 — Ki = 251.19 nM 6.60
CHEMBL1978448 — Ki = 251.19 nM 6.60
CHEMBL1992634 — Ki = 316.23 nM 6.50
CHEMBL522892 DOVITINIB Ki = 316.23 nM 6.50
CHEMBL1986855 — Ki = 316.23 nM 6.50
CHEMBL1968930 — Ki = 316.23 nM 6.50
CHEMBL458997 — Ki = 316.23 nM 6.50
CHEMBL1980253 — Ki = 398.11 nM 6.40
CHEMBL379975 — Ki = 398.11 nM 6.40
CHEMBL1980562 — Ki = 398.11 nM 6.40
CHEMBL1987261 — Ki = 398.11 nM 6.40