Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL1963758

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: FES
ChEMBL ↗
399
Total Activities
390
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Category other
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Tyrosine-protein kinase Fes/Fps (CHEMBL5455) ↗
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

PubChem BioAssay data set

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 399 6.40 8.10

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL244378 — — 1 8.10
CHEMBL396523 — — 1 8.00
CHEMBL243088 — — 1 8.00
CHEMBL1983111 — — 1 7.90
CHEMBL1981047 — — 1 7.70
CHEMBL1988163 — — 1 7.50
CHEMBL1987034 — — 1 7.40
CHEMBL1989708 — — 2 7.30
CHEMBL1825138 — — 1 7.30
CHEMBL1725279 SP-600125 — 1 7.10
CHEMBL1986263 — — 1 6.90
CHEMBL1990885 — — 1 6.90
CHEMBL458997 — — 1 6.90
CHEMBL1978448 — — 1 6.80
CHEMBL1974664 — — 1 6.80
CHEMBL1967720 — — 1 6.70
CHEMBL1993941 — — 1 6.60
CHEMBL1970104 — — 2 6.60
CHEMBL1972142 — — 1 6.60
CHEMBL1975490 — — 1 6.60
CHEMBL1972584 — — 2 6.50
CHEMBL2000393 — — 1 6.50
CHEMBL1980896 — — 1 6.50
CHEMBL491758 — — 1 6.50
CHEMBL2000568 — — 1 6.40
CHEMBL1968380 — — 1 6.40
CHEMBL1977681 — — 1 6.40
CHEMBL1971943 BAY-549 — 1 6.40
CHEMBL371206 — — 1 6.40
CHEMBL2002165 — — 1 6.30

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL244378 — Ki = 7.943 nM 8.10
CHEMBL243088 — Ki = 10.0 nM 8.00
CHEMBL396523 — Ki = 10.0 nM 8.00
CHEMBL1983111 — Ki = 12.59 nM 7.90
CHEMBL1981047 — Ki = 19.95 nM 7.70
CHEMBL1988163 — Ki = 31.62 nM 7.50
CHEMBL1987034 — Ki = 39.81 nM 7.40
CHEMBL1989708 — Ki = 50.12 nM 7.30
CHEMBL1825138 — Ki = 50.12 nM 7.30
CHEMBL1725279 SP-600125 Ki = 79.43 nM 7.10
CHEMBL458997 — Ki = 125.89 nM 6.90
CHEMBL1990885 — Ki = 125.89 nM 6.90
CHEMBL1986263 — Ki = 125.89 nM 6.90
CHEMBL1989708 — Ki = 158.49 nM 6.80
CHEMBL1978448 — Ki = 158.49 nM 6.80
CHEMBL1974664 — Ki = 158.49 nM 6.80
CHEMBL1967720 — Ki = 199.53 nM 6.70
CHEMBL1993941 — Ki = 251.19 nM 6.60
CHEMBL1970104 — Ki = 251.19 nM 6.60
CHEMBL1970104 — Ki = 251.19 nM 6.60
CHEMBL1975490 — Ki = 251.19 nM 6.60
CHEMBL1972142 — Ki = 251.19 nM 6.60
CHEMBL491758 — Ki = 316.23 nM 6.50
CHEMBL1972584 — Ki = 316.23 nM 6.50
CHEMBL2000393 — Ki = 316.23 nM 6.50
CHEMBL1972584 — Ki = 316.23 nM 6.50
CHEMBL1980896 — Ki = 316.23 nM 6.50
CHEMBL2000568 — Ki = 398.11 nM 6.40
CHEMBL371206 — Ki = 398.11 nM 6.40
CHEMBL1971943 BAY-549 Ki = 398.11 nM 6.40
CHEMBL1977681 — Ki = 398.11 nM 6.40
CHEMBL1968380 — Ki = 398.11 nM 6.40
CHEMBL1090356 — Ki = 501.19 nM 6.30
CHEMBL1988594 — Ki = 501.19 nM 6.30
CHEMBL2002165 — Ki = 501.19 nM 6.30
CHEMBL1982957 — Ki = 501.19 nM 6.30
CHEMBL1974254 — Ki = 501.19 nM 6.30
CHEMBL1682552 — Ki = 630.96 nM 6.20
CHEMBL508928 — Ki = 630.96 nM 6.20
CHEMBL1992634 — Ki = 630.96 nM 6.20
CHEMBL1996817 — Ki = 630.96 nM 6.20
CHEMBL1986943 — Ki = 794.33 nM 6.10
CHEMBL1986943 — Ki = 794.33 nM 6.10
CHEMBL1979516 — Ki = 794.33 nM 6.10
CHEMBL1998585 — Ki = 794.33 nM 6.10
CHEMBL271381 — Ki = 1000.0 nM 6.00
CHEMBL1983309 — Ki = 1000.0 nM 6.00
CHEMBL583144 — Ki = 1000.0 nM 6.00
CHEMBL1988075 — Ki = 1000.0 nM 6.00
CHEMBL1965507 — Ki = 1000.0 nM 6.00