| Proto-oncogene tyrosine-protein kinase receptor Ret CHEMBL2041 | Ki | 6.9 | 6.9 | 125.9 | 1 |
| Rho-associated protein kinase 2 CHEMBL2973 | Ki | 6.6 | 6.6 | 251.2 | 1 |
| Casein kinase I isoform alpha CHEMBL2793 | Ki | 6.6 | 6.6 | 251.2 | 1 |
| Tyrosine-protein kinase Fes/Fps CHEMBL5455 | Ki | 6.6 | 6.6 | 251.2 | 1 |
| Ribosomal protein S6 kinase alpha-3 CHEMBL2345 | Ki | 6.5 | 6.5 | 316.2 | 1 |
| Maternal embryonic leucine zipper kinase CHEMBL4578 | Ki | 6.4 | 6.4 | 398.1 | 1 |
| Rho-associated protein kinase 1 CHEMBL3231 | Ki | 6.4 | 6.4 | 398.1 | 1 |
| Homeodomain-interacting protein kinase 2 CHEMBL4576 | Ki | 6.1 | 6.1 | 794.3 | 1 |
| Dual specificity protein kinase CLK4 CHEMBL4203 | Ki | 6.1 | 6.1 | 794.3 | 1 |
| Tyrosine-protein kinase Lck CHEMBL258 | Ki | 6.1 | 6.1 | 794.3 | 1 |
| Aurora kinase B CHEMBL2185 | Ki | 6.0 | 6.0 | 1000.0 | 1 |
| Receptor-type tyrosine-protein kinase FLT3 CHEMBL1974 | Ki | 6.0 | 6.0 | 1000.0 | 1 |
| Serine/threonine-protein kinase pim-3 CHEMBL5407 | Ki | 6.0 | 6.0 | 1000.0 | 1 |
| Calcium/calmodulin-dependent protein kinase type II subunit gamma CHEMBL3829 | Ki | 6.0 | 6.0 | 1000.0 | 1 |
| Ephrin type-A receptor 2 CHEMBL2068 | Ki | 5.9 | 5.9 | 1258.9 | 1 |
| Serine/threonine-protein kinase pim-1 CHEMBL2147 | Ki | 5.8 | 5.8 | 1584.9 | 1 |
| Serine/threonine-protein kinase TAO1 CHEMBL5261 | Ki | 5.8 | 5.8 | 1584.9 | 1 |
| Ribosomal protein S6 kinase beta-1 CHEMBL4501 | Ki | 5.7 | 5.7 | 1995.3 | 1 |
| Cyclin-dependent kinase 2 CHEMBL301 | Ki | 5.7 | 5.7 | 1995.3 | 1 |
| Casein kinase I isoform delta CHEMBL2828 | Ki | 5.6 | 5.6 | 2511.9 | 1 |
| Serine/threonine-protein kinase 17A CHEMBL4525 | Ki | 5.6 | 5.6 | 2511.9 | 1 |
| Homeodomain-interacting protein kinase 4 CHEMBL1075167 | Ki | 5.6 | 5.6 | 2511.9 | 1 |
| Serine/threonine-protein kinase Nek2 CHEMBL3835 | Ki | 5.5 | 5.5 | 3162.3 | 1 |
| Protein kinase C delta type CHEMBL2996 | Ki | 5.5 | 5.5 | 3162.3 | 1 |
| Interleukin-1 receptor-associated kinase 4 CHEMBL3778 | Ki | 5.5 | 5.5 | 3162.3 | 1 |
| Protein kinase C iota type CHEMBL2598 | Ki | 5.5 | 5.5 | 3162.3 | 1 |
| Casein kinase I isoform gamma-2 CHEMBL2543 | Ki | 5.5 | 5.5 | 3162.3 | 1 |
| Serine/threonine-protein kinase PLK4 CHEMBL3788 | Ki | 5.4 | 5.4 | 3981.1 | 1 |
| Mitogen-activated protein kinase kinase kinase kinase 2 CHEMBL5330 | Ki | 5.4 | 5.4 | 3981.1 | 1 |
| Calcium/calmodulin-dependent protein kinase type 1 CHEMBL2493 | Ki | 5.4 | 5.4 | 3981.1 | 1 |
| Serine/threonine-protein kinase Chk1 CHEMBL4630 | Ki | 5.4 | 5.4 | 3981.1 | 1 |
| Calcium/calmodulin-dependent protein kinase type II subunit delta CHEMBL2801 | Ki | 5.3 | 5.3 | 5011.9 | 1 |
| Serine/threonine-protein kinase D3 CHEMBL2595 | Ki | 5.3 | 5.3 | 5011.9 | 1 |
| Serine/threonine-protein kinase MRCK alpha CHEMBL4516 | Ki | 5.3 | 5.3 | 5011.9 | 1 |
| Insulin receptor CHEMBL1981 | Ki | 5.3 | 5.3 | 5011.9 | 1 |
| Vascular endothelial growth factor receptor 3 CHEMBL1955 | Ki | 5.2 | 5.2 | 6309.6 | 1 |
| Serine/threonine-protein kinase Nek4 CHEMBL5819 | Ki | 5.2 | 5.2 | 6309.6 | 1 |
| Casein kinase I isoform gamma-3 CHEMBL5084 | Ki | 5.2 | 5.2 | 6309.6 | 1 |
| Serine/threonine-protein kinase D2 CHEMBL4900 | Ki | 5.2 | 5.2 | 6309.6 | 1 |
| Calcium/calmodulin-dependent protein kinase type II subunit beta CHEMBL4121 | Ki | 5.2 | 5.2 | 6309.6 | 1 |
| Protein kinase C gamma type CHEMBL2938 | Ki | 5.2 | 5.2 | 6309.6 | 1 |
| Serine/threonine-protein kinase 3 CHEMBL4708 | Ki | 5.1 | 5.1 | 7943.3 | 1 |
| STE20-like serine/threonine-protein kinase CHEMBL4202 | Ki | 5.1 | 5.1 | 7943.3 | 1 |
| Cyclin-dependent kinase 5 CHEMBL4036 | Ki | 5.1 | 5.1 | 7943.3 | 1 |
| Serine/threonine-protein kinase N2 CHEMBL3032 | Ki | 5.1 | 5.1 | 7943.3 | 1 |
| Serine/threonine-protein kinase Sgk2 CHEMBL5794 | Ki | 5.1 | 5.1 | 7943.3 | 1 |
| Mitogen-activated protein kinase kinase kinase kinase 4 CHEMBL6166 | Ki | 5.1 | 5.1 | 7943.3 | 1 |