Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL1963710

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: CAMK2G
ChEMBL ↗
592
Total Activities
579
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Category other
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Calcium/calmodulin-dependent protein kinase type II subunit gamma (CHEMBL3829) ↗
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

PubChem BioAssay data set

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 592 5.87 8.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1966628 — — 1 8.40
CHEMBL1974870 — — 2 8.40
CHEMBL1998159 — — 1 8.00
CHEMBL509032 TAE-684 — 1 7.90
CHEMBL1970903 — — 1 7.90
CHEMBL1991063 — — 1 7.80
CHEMBL2001751 — — 1 7.60
CHEMBL2002726 — — 1 7.60
CHEMBL1986943 — — 2 7.50
CHEMBL1990885 — — 1 7.40
CHEMBL1993661 — — 1 7.40
CHEMBL1965836 — — 1 7.30
CHEMBL1982957 — — 1 7.30
CHEMBL1996817 — — 1 7.30
CHEMBL1987034 — — 1 7.20
CHEMBL565612 SOTRASTAURIN 2.0 1 7.10
CHEMBL1995813 — — 1 7.10
CHEMBL1969588 — — 1 7.00
CHEMBL1988163 — — 1 6.90
CHEMBL1967878 CENISERTIB 2.0 1 6.80
CHEMBL1988537 — — 1 6.80
CHEMBL1992922 — — 1 6.70
CHEMBL1973540 — — 1 6.70
CHEMBL1982711 — — 1 6.70
CHEMBL1968380 — — 1 6.70
CHEMBL1983111 — — 1 6.60
CHEMBL2000071 — — 1 6.60
CHEMBL1978448 — — 1 6.60
CHEMBL398951 — — 1 6.50
CHEMBL1991078 — — 1 6.50

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1966628 — Ki = 3.981 nM 8.40
CHEMBL1974870 — Ki = 3.981 nM 8.40
CHEMBL1974870 — Ki = 3.981 nM 8.40
CHEMBL1998159 — Ki = 10.0 nM 8.00
CHEMBL509032 TAE-684 Ki = 12.59 nM 7.90
CHEMBL1970903 — Ki = 12.59 nM 7.90
CHEMBL1991063 — Ki = 15.85 nM 7.80
CHEMBL2002726 — Ki = 25.12 nM 7.60
CHEMBL2001751 — Ki = 25.12 nM 7.60
CHEMBL1986943 — Ki = 31.62 nM 7.50
CHEMBL1986943 — Ki = 31.62 nM 7.50
CHEMBL1993661 — Ki = 39.81 nM 7.40
CHEMBL1990885 — Ki = 39.81 nM 7.40
CHEMBL1982957 — Ki = 50.12 nM 7.30
CHEMBL1996817 — Ki = 50.12 nM 7.30
CHEMBL1965836 — Ki = 50.12 nM 7.30
CHEMBL1987034 — Ki = 63.1 nM 7.20
CHEMBL1995813 — Ki = 79.43 nM 7.10
CHEMBL565612 SOTRASTAURIN Ki = 79.43 nM 7.10
CHEMBL1969588 — Ki = 100.0 nM 7.00
CHEMBL1988163 — Ki = 125.89 nM 6.90
CHEMBL1967878 CENISERTIB Ki = 158.49 nM 6.80
CHEMBL1988537 — Ki = 158.49 nM 6.80
CHEMBL1992922 — Ki = 199.53 nM 6.70
CHEMBL1968380 — Ki = 199.53 nM 6.70
CHEMBL1973540 — Ki = 199.53 nM 6.70
CHEMBL1982711 — Ki = 199.53 nM 6.70
CHEMBL1983111 — Ki = 251.19 nM 6.60
CHEMBL1978448 — Ki = 251.19 nM 6.60
CHEMBL2000071 — Ki = 251.19 nM 6.60
CHEMBL1992634 — Ki = 316.23 nM 6.50
CHEMBL1993424 — Ki = 316.23 nM 6.50
CHEMBL1991078 — Ki = 316.23 nM 6.50
CHEMBL398951 — Ki = 316.23 nM 6.50
CHEMBL1999931 — Ki = 316.23 nM 6.50
CHEMBL1986263 — Ki = 316.23 nM 6.50
CHEMBL1974328 — Ki = 398.11 nM 6.40
CHEMBL1967887 — Ki = 398.11 nM 6.40
CHEMBL475251 R-406 Ki = 398.11 nM 6.40
CHEMBL2001920 — Ki = 501.19 nM 6.30
CHEMBL2006439 — Ki = 501.19 nM 6.30
CHEMBL2000393 — Ki = 501.19 nM 6.30
CHEMBL2003638 — Ki = 501.19 nM 6.30
CHEMBL592030 — Ki = 501.19 nM 6.30
CHEMBL1996979 — Ki = 501.19 nM 6.30
CHEMBL2000335 — Ki = 501.19 nM 6.30
CHEMBL371206 — Ki = 501.19 nM 6.30
CHEMBL244378 — Ki = 630.96 nM 6.20
CHEMBL392642 — Ki = 630.96 nM 6.20
CHEMBL1982924 — Ki = 630.96 nM 6.20