Compound Detail
CHEMBL1983309
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Basic Information
| ChEMBL ID | CHEMBL1983309 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UNVKXVCDLOLPJE-UHFFFAOYSA-N |
15
Targets
15
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
348.8
MW (Da)
4.22
ALogP
5
HBA
1
HBD
60.5
PSA (Ų)
0.77
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 15 meas. best 6.3
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glycogen synthase kinase-3 beta CHEMBL262 | Ki | 6.3 | 6.3 | 501.2 | 1 |
| Aurora kinase B CHEMBL2185 | Ki | 6.2 | 6.2 | 631.0 | 1 |
| Mitogen-activated protein kinase kinase kinase kinase 2 CHEMBL5330 | Ki | 6.2 | 6.2 | 631.0 | 1 |
| Serine/threonine-protein kinase DCLK1 CHEMBL5683 | Ki | 6.2 | 6.2 | 631.0 | 1 |
| NT-3 growth factor receptor CHEMBL5608 | Ki | 6.1 | 6.1 | 794.3 | 1 |
| Glycogen synthase kinase-3 alpha CHEMBL2850 | Ki | 6.0 | 6.0 | 1000.0 | 1 |
| Dual specificity protein kinase CLK4 CHEMBL4203 | Ki | 6.0 | 6.0 | 1000.0 | 1 |
| Tyrosine-protein kinase Fes/Fps CHEMBL5455 | Ki | 6.0 | 6.0 | 1000.0 | 1 |
| Homeodomain-interacting protein kinase 4 CHEMBL1075167 | Ki | 5.8 | 5.8 | 1584.9 | 1 |
| Cyclin-dependent kinase 2 CHEMBL301 | Ki | 5.5 | 5.5 | 3162.3 | 1 |
| Mitogen-activated protein kinase kinase kinase kinase 5 CHEMBL4852 | Ki | 5.5 | 5.5 | 3162.3 | 1 |
| Casein kinase I isoform gamma-3 CHEMBL5084 | Ki | 5.5 | 5.5 | 3162.3 | 1 |
| Serine/threonine-protein kinase 17A CHEMBL4525 | Ki | 5.4 | 5.4 | 3981.1 | 1 |
| Serine/threonine-protein kinase pim-1 CHEMBL2147 | Ki | 5.2 | 5.2 | 6309.6 | 1 |
| Interleukin-1 receptor-associated kinase 1 CHEMBL3357 | Ki | 5.1 | 5.1 | 7943.3 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine