Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL1963776

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: CHUK
ChEMBL ↗
297
Total Activities
293
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Category other
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Inhibitor of nuclear factor kappa-B kinase subunit alpha (CHEMBL3476) ↗
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

PubChem BioAssay data set

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 297 5.99 7.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1980995 — — 1 7.30
CHEMBL260092 — — 1 7.00
CHEMBL1997129 — — 1 6.90
CHEMBL590109 — — 1 6.80
CHEMBL1986263 — — 1 6.60
CHEMBL1970903 — — 1 6.50
CHEMBL2001751 — — 1 6.40
CHEMBL2000685 — — 1 6.30
CHEMBL1991728 — — 1 6.30
CHEMBL1983945 — — 1 6.20
CHEMBL1974935 — — 1 6.20
CHEMBL2000071 — — 1 6.10
CHEMBL1994361 — — 1 6.00
CHEMBL1682346 — — 1 6.00
CHEMBL1975418 — — 1 6.00
CHEMBL1989518 — — 1 5.90
CHEMBL1980715 LAUROGUADINE 2.0 1 5.90
CHEMBL1977223 — — 1 5.90
CHEMBL1972840 — — 1 5.80
CHEMBL1973937 — — 1 5.80
CHEMBL504950 — — 1 5.80
CHEMBL1991846 — — 1 5.80
CHEMBL1966087 — — 1 5.80
CHEMBL1965495 — — 1 5.70
CHEMBL1970104 — — 2 5.70
CHEMBL1996817 — — 1 5.70
CHEMBL2007064 — — 1 5.70
CHEMBL1682345 — — 1 5.60
CHEMBL1992922 — — 1 5.60
CHEMBL1991640 — — 1 5.60

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1980995 — Ki = 50.12 nM 7.30
CHEMBL260092 — Ki = 100.0 nM 7.00
CHEMBL1997129 — Ki = 125.89 nM 6.90
CHEMBL590109 — Ki = 158.49 nM 6.80
CHEMBL1986263 — Ki = 251.19 nM 6.60
CHEMBL1970903 — Ki = 316.23 nM 6.50
CHEMBL2001751 — Ki = 398.11 nM 6.40
CHEMBL2000685 — Ki = 501.19 nM 6.30
CHEMBL1991728 — Ki = 501.19 nM 6.30
CHEMBL1974935 — Ki = 630.96 nM 6.20
CHEMBL1983945 — Ki = 630.96 nM 6.20
CHEMBL2000071 — Ki = 794.33 nM 6.10
CHEMBL1975418 — Ki = 1000.0 nM 6.00
CHEMBL1994361 — Ki = 1000.0 nM 6.00
CHEMBL1682346 — Ki = 1000.0 nM 6.00
CHEMBL1980715 LAUROGUADINE Ki = 1258.93 nM 5.90
CHEMBL1989518 — Ki = 1258.93 nM 5.90
CHEMBL1977223 — Ki = 1258.93 nM 5.90
CHEMBL1973937 — Ki = 1584.89 nM 5.80
CHEMBL1972840 — Ki = 1584.89 nM 5.80
CHEMBL1991846 — Ki = 1584.89 nM 5.80
CHEMBL1966087 — Ki = 1584.89 nM 5.80
CHEMBL504950 — Ki = 1584.89 nM 5.80
CHEMBL1996817 — Ki = 1995.26 nM 5.70
CHEMBL1970104 — Ki = 1995.26 nM 5.70
CHEMBL1970104 — Ki = 1995.26 nM 5.70
CHEMBL1965495 — Ki = 1995.26 nM 5.70
CHEMBL2007064 — Ki = 1995.26 nM 5.70
CHEMBL2002726 — Ki = 2511.89 nM 5.60
CHEMBL2000271 — Ki = 2511.89 nM 5.60
CHEMBL1682345 — Ki = 2511.89 nM 5.60
CHEMBL1992922 — Ki = 2511.89 nM 5.60
CHEMBL1991640 — Ki = 2511.89 nM 5.60
CHEMBL1991180 — Ki = 3162.28 nM 5.50
CHEMBL1994526 — Ki = 3162.28 nM 5.50
CHEMBL1241473 — Ki = 3162.28 nM 5.50
CHEMBL1682341 — Ki = 3981.07 nM 5.40
CHEMBL336961 AZAKENPAULLONE Ki > 3981.07 nM -
CHEMBL1970522 — Ki > 3981.07 nM -
CHEMBL402846 — Ki > 3981.07 nM -
CHEMBL394619 — Ki > 3981.07 nM -
CHEMBL1964413 — Ki > 3981.07 nM -
CHEMBL1970083 — Ki > 3981.07 nM -
CHEMBL1996390 — Ki > 3981.07 nM -
CHEMBL1984432 — Ki > 3981.07 nM -
CHEMBL219722 — Ki > 3981.07 nM -
CHEMBL1381197 — Ki > 3981.07 nM -
CHEMBL2003817 — Ki > 3981.07 nM -
CHEMBL1990885 — Ki > 3981.07 nM -
CHEMBL1965988 — Ki > 3981.07 nM -