Compound Detail
CHEMBL1996390
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Basic Information
| ChEMBL ID | CHEMBL1996390 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | WICLISNBDMGFST-UHFFFAOYSA-N |
19
Targets
19
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
255.3
MW (Da)
3.66
ALogP
3
HBA
1
HBD
50.2
PSA (Ų)
0.76
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 19 meas. best 6.8
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Death-associated protein kinase 3 CHEMBL2468 | Ki | 6.8 | 6.8 | 158.5 | 1 |
| Serine/threonine-protein kinase pim-2 CHEMBL4523 | Ki | 6.7 | 6.7 | 199.5 | 1 |
| Glycogen synthase kinase-3 beta CHEMBL262 | Ki | 6.4 | 6.4 | 398.1 | 1 |
| Serine/threonine-protein kinase PLK4 CHEMBL3788 | Ki | 6.4 | 6.4 | 398.1 | 1 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1A CHEMBL2292 | Ki | 6.3 | 6.3 | 501.2 | 1 |
| Serine/threonine-protein kinase Chk2 CHEMBL2527 | Ki | 6.3 | 6.3 | 501.2 | 1 |
| Glycogen synthase kinase-3 alpha CHEMBL2850 | Ki | 6.2 | 6.2 | 631.0 | 1 |
| Serine/threonine-protein kinase pim-1 CHEMBL2147 | Ki | 6.1 | 6.1 | 794.3 | 1 |
| Casein kinase I isoform delta CHEMBL2828 | Ki | 6.1 | 6.1 | 794.3 | 1 |
| Aurora kinase A CHEMBL4722 | Ki | 6.0 | 6.0 | 1000.0 | 1 |
| Casein kinase II subunit alpha CHEMBL3629 | Ki | 5.9 | 5.9 | 1258.9 | 1 |
| Aurora kinase B CHEMBL2185 | Ki | 5.8 | 5.8 | 1584.9 | 1 |
| Mitogen-activated protein kinase 9 CHEMBL4179 | Ki | 5.7 | 5.7 | 1995.3 | 1 |
| Serine/threonine-protein kinase PLK3 CHEMBL4897 | Ki | 5.6 | 5.6 | 2511.9 | 1 |
| Cyclin-dependent kinase 1 CHEMBL308 | Ki | 5.5 | 5.5 | 3162.3 | 1 |
| Serine/threonine-protein kinase Sgk2 CHEMBL5794 | Ki | 5.4 | 5.4 | 3981.1 | 1 |
| Ribosomal protein S6 kinase alpha-3 CHEMBL2345 | Ki | 5.4 | 5.4 | 3981.1 | 1 |
| cAMP-dependent protein kinase catalytic subunit alpha CHEMBL4101 | Ki | 5.1 | 5.1 | 7943.3 | 1 |
| Cyclin-dependent kinase 2 CHEMBL301 | Ki | 5.1 | 5.1 | 7943.3 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine