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Compound Detail

CHEMBL1315921

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COc1ccc(-[n+]2c(-c3ccccc3)cc(-c3ccccc3)cc2-c2ccccc2)cc1.[O-][Cl+3]([O-])([O-])[O-]

Basic Information

ChEMBL ID CHEMBL1315921
Phase Preclinical
Structure Type MOL
InChI Key VTQDBZFUSCKGAZ-UHFFFAOYSA-M
Parent Compound CHEMBL1617400
Active Moiety CHEMBL1617400
2
Targets
7
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

414.5
MW (Da)
6.97
ALogP
1
HBA
0
HBD
13.1
PSA (Ų)
0.28
QED
1
Ro5 Violations
5
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C30H24ClNO5
MW 513.98
Aromatic Rings 5
Heavy Atoms 32
NP-Likeness -0.35

Activity Summary

EC50 7 meas. best 7.34

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Unchecked
CHEMBL612545
EC50 7.34 5.258 46.0 5
BJ
CHEMBL614358
EC50 4.93 4.89 11657.0 2

Activity Data Samples

Top measurements by pChEMBL value

Data from ChEMBL 36 via Core Engine