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Compound Detail

CHEMBL1334456

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CC(=O)O[C@H]1C[C@@]2(C)[C@@H](C[C@@H](O)[C@H]3[C@@]4(C)CC[C@@H](O)[C@@H](C)[C@@H]4CC[C@@]32C)/C1=C(/CCC=C(C)C)C(=O)O

Basic Information

ChEMBL ID CHEMBL1334456
Phase Preclinical
Structure Type MOL
InChI Key IECPWNUMDGFDKC-UEVMROTKSA-N
4
Targets
6
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

516.7
MW (Da)
5.67
ALogP
5
HBA
3
HBD
104.1
PSA (Ų)
0.25
QED
2
Ro5 Violations
5
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C31H48O6
MW 516.72
Aromatic Rings 0
Heavy Atoms 37
NP-Likeness 3.08

Activity Summary

EC50 4 meas. best 6.79
IC50 2 meas. best 5.8

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Streptococcus sp. 'group A'
CHEMBL612389
EC50 6.79 6.79 161.0 1
Streptokinase A
CHEMBL1293228
EC50 6.75 6.595 177.0 2
Streptococcus
CHEMBL612313
EC50 6.02 6.02 947.0 1
Unchecked
CHEMBL612545
IC50 5.8 5.665 1600.0 2

Activity Data Samples

Top measurements by pChEMBL value

Data from ChEMBL 36 via Core Engine