Compound Detail
CHEMBL1361703
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Basic Information
| ChEMBL ID | CHEMBL1361703 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | LHUVKNSYJXRVJA-UHFFFAOYSA-N |
8
Targets
10
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
416.4
MW (Da)
3.98
ALogP
6
HBA
1
HBD
90.7
PSA (Ų)
0.46
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 10 meas. best 5.69
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Induced myeloid leukemia cell differentiation protein Mcl-1 CHEMBL4361 | IC50 | 5.69 | 5.69 | 2041.0 | 1 |
| SUMO-activating enzyme CHEMBL2095174 | IC50 | 5.27 | 5.12 | 5420.0 | 2 |
| SUMO E1/E2 CHEMBL3137290 | IC50 | 5.24 | 5.24 | 5800.0 | 1 |
| Protein-tyrosine kinase 2-beta CHEMBL5469 | IC50 | 5.24 | 5.24 | 5794.0 | 1 |
| DNA (cytosine-5)-methyltransferase 1 CHEMBL1993 | IC50 | 5.15 | 5.15 | 7110.0 | 1 |
| Voltage-gated N-type calcium channel alpha-1B subunit/Amyloid beta A4 precursor protein-binding family A member 1 CHEMBL2097170 | IC50 | 5.11 | 4.875 | 7830.0 | 2 |
| Nuclear receptor subfamily 4immunitygroup A member 1 CHEMBL1293229 | IC50 | 4.97 | 4.97 | 10713.0 | 1 |
| Unchecked CHEMBL612545 | IC50 | 4.22 | 4.22 | 60200.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine