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Compound Detail

CHEMBL1987938

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COc1ccc(C(=O)N/N=C(\C)c2ccccn2)cc1OC

Basic Information

ChEMBL ID CHEMBL1987938
Phase Preclinical
Structure Type MOL
InChI Key RVSZFFNLOBBBAT-WOJGMQOQSA-N
2
Targets
7
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

299.3
MW (Da)
2.25
ALogP
5
HBA
1
HBD
72.8
PSA (Ų)
0.68
QED
0
Ro5 Violations
5
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C16H17N3O3
MW 299.33
Aromatic Rings 2
Heavy Atoms 22
NP-Likeness -1.42

Activity Summary

EC50 6 meas. best 5.91
IC50 1 meas. best 6.03

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Unchecked
CHEMBL612545
IC50 6.03 6.03 936.8 1
BJ
CHEMBL614358
EC50 5.91 5.4975 1230.0 4
Unchecked
CHEMBL612545
EC50 5.55 5.4 2820.0 2

Activity Data Samples

Top measurements by pChEMBL value

Data from ChEMBL 36 via Core Engine