Compound Detail
CHEMBL2369184
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Basic Information
| ChEMBL ID | CHEMBL2369184 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | GXFFVQWGMMQOAK-NSFLPQOVSA-N |
4
Targets
6
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
387.7
MW (Da)
5.20
ALogP
4
HBA
3
HBD
73.7
PSA (Ų)
0.29
QED
1
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 6 meas. best 5.9
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Streptococcus sp. 'group A' CHEMBL612389 | EC50 | 5.9 | 5.9 | 1259.0 | 1 |
| Unchecked CHEMBL612545 | EC50 | 5.88 | 5.3433 | 1323.0 | 3 |
| Streptokinase A CHEMBL1293228 | EC50 | 5.87 | 5.87 | 1360.0 | 1 |
| Streptococcus CHEMBL612313 | EC50 | 5.41 | 5.41 | 3932.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Streptococcus sp. 'group A' | EC50 | = | 1259.0 | nM | 5.9 | PUBCHEM_BIOASSAY: Luminescence Microorganism-Based Dose Confirmation HTS to Iden... | - |
| Unchecked | EC50 | = | 1323.0 | nM | 5.88 | PUBCHEM_BIOASSAY: Luminescence Cell-Based/Microorganism Dose Confirmation HTS to... | - |
| Streptokinase A | EC50 | = | 1360.0 | nM | 5.87 | PUBCHEM_BIOASSAY: Luminescence Microorganism-Based Dose Confirmation HTS to Iden... | - |
| Streptococcus | EC50 | = | 3932.0 | nM | 5.41 | PUBCHEM_BIOASSAY: Luminescence Microorganism-Based Dose Response HTS to Identify... | - |
| Unchecked | EC50 | = | 4060.0 | nM | 5.39 | PUBCHEM_BIOASSAY: Dose response confirmation of small molecule activators of the... | - |
| Unchecked | EC50 | = | 17300.0 | nM | 4.76 | PUBCHEM_BIOASSAY: Dose response counterscreen for uHTS small molecule activators... | - |
Data from ChEMBL 36 via Core Engine