Compound Detail
CHEMBL4095667
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Basic Information
| ChEMBL ID | CHEMBL4095667 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FBAMZGIGIXSVJK-UHFFFAOYSA-N |
11
Targets
11
Activities
1
Assay Types
0
PK Parameters
16
Publications
0
Known Names
Molecular Properties
293.3
MW (Da)
2.97
ALogP
4
HBA
3
HBD
74.2
PSA (Ų)
0.51
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 11 meas. best 9.1
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Histone deacetylase 6 CHEMBL1865 | IC50 | 9.1 | 9.1 | 0.8 | 1 |
| Histone deacetylase 8 CHEMBL3192 | IC50 | 6.2 | 6.2 | 636.0 | 1 |
| Histone deacetylase 7 CHEMBL2716 | IC50 | 6.12 | 6.12 | 766.0 | 1 |
| Histone deacetylase 11 CHEMBL3310 | IC50 | 6.0 | 6.0 | 1004.0 | 1 |
| Polyamine deacetylase HDAC10 CHEMBL5103 | IC50 | 5.9 | 5.9 | 1256.0 | 1 |
| Histone deacetylase 9 CHEMBL4145 | IC50 | 5.72 | 5.72 | 1915.0 | 1 |
| Histone deacetylase 5 CHEMBL2563 | IC50 | 5.65 | 5.65 | 2251.0 | 1 |
| Histone deacetylase 4 CHEMBL3524 | IC50 | 5.32 | 5.32 | 4817.0 | 1 |
| Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2) CHEMBL2111363 | IC50 | 5.26 | 5.26 | 5480.0 | 1 |
| Histone deacetylase 1 CHEMBL325 | IC50 | 5.15 | 5.15 | 7050.0 | 1 |
| Histone deacetylase 2 CHEMBL1937 | IC50 | 5.07 | 5.07 | 8610.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Literature References
Data from ChEMBL 36 via Core Engine