Compound Detail
CHEMBL1322948
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Basic Information
| ChEMBL ID | CHEMBL1322948 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | YGEAMKXNJBSFEW-UHFFFAOYSA-N |
6
Targets
7
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
318.4
MW (Da)
3.34
ALogP
5
HBA
2
HBD
92.5
PSA (Ų)
0.38
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 5 meas. best 5.63
EC50 2 meas. best 7.34
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | EC50 | 7.34 | 7.34 | 46.0 | 1 |
| Corticotropin-releasing factor receptor 2/Corticotropin-releasing factor-binding protein CHEMBL3885546 | IC50 | 5.63 | 5.63 | 2340.0 | 1 |
| Caspase-3 CHEMBL2334 | IC50 | 4.75 | 4.75 | 17900.0 | 1 |
| Corticotropin-releasing factor receptor 2/Corticotropin-releasing factor-binding protein CHEMBL3885546 | EC50 | 4.63 | 4.63 | 23400.0 | 1 |
| Sentrin-specific protease 6 CHEMBL1741215 | IC50 | 4.59 | 4.59 | 25600.0 | 1 |
| Sentrin-specific protease 7 CHEMBL1741213 | IC50 | 4.53 | 4.53 | 29300.0 | 1 |
| Sentrin-specific protease 8 CHEMBL1741207 | IC50 | 4.5 | 4.5 | 31300.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine