Compound Detail
CHEMBL1360793
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Basic Information
| ChEMBL ID | CHEMBL1360793 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | INVDZMLQVYHNCX-PKNBQFBNSA-N |
3
Targets
8
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
373.4
MW (Da)
4.37
ALogP
6
HBA
0
HBD
91.2
PSA (Ų)
0.39
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 8 meas. best 6.26
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | EC50 | 6.26 | 5.66 | 552.0 | 4 |
| BJ CHEMBL614358 | EC50 | 5.43 | 5.34 | 3691.0 | 3 |
| Endoribonuclease toxin MazF CHEMBL1795096 | EC50 | 5.08 | 5.08 | 8270.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | EC50 | = | 552.0 | nM | 6.26 | PUBCHEM_BIOASSAY: High Throughput Screen to Identify Compounds that Suppress the... | - |
| Unchecked | EC50 | = | 610.0 | nM | 6.21 | PUBCHEM_BIOASSAY: High Throughput Screen to Identify Compounds that Suppress the... | - |
| BJ | EC50 | = | 3691.0 | nM | 5.43 | PUBCHEM_BIOASSAY: Luminescence Cell-Based Dose Response HTS to Identify Compound... | - |
| BJ | EC50 | = | 4859.0 | nM | 5.31 | PUBCHEM_BIOASSAY: Luminescence Cell-Based Dose Confirmation HTS to Identify Comp... | - |
| BJ | EC50 | = | 5281.0 | nM | 5.28 | PUBCHEM_BIOASSAY: Luminescence Cell-Based Dose Response HTS to Identify Compound... | - |
| Unchecked | EC50 | = | 5823.0 | nM | 5.24 | PUBCHEM_BIOASSAY: Luminescence Cell-Based Dose Response HTS to Identify Compound... | - |
| Endoribonuclease toxin MazF | EC50 | = | 8270.0 | nM | 5.08 | PUBCHEM_BIOASSAY: Dose response confirmation uHTS hits for MazEF TA System activ... | - |
| Unchecked | EC50 | = | 11700.0 | nM | 4.93 | PUBCHEM_BIOASSAY: Dose response confirmation of small molecule activators of the... | - |
Data from ChEMBL 36 via Core Engine