Compound Detail
CHEMBL1432707
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Basic Information
| ChEMBL ID | CHEMBL1432707 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FKVLEVTZACLFAJ-UHFFFAOYSA-N |
9
Targets
13
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
316.3
MW (Da)
0.62
ALogP
7
HBA
0
HBD
85.8
PSA (Ų)
0.58
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 10 meas. best 6.0
EC50 3 meas. best 6.7
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Protein RecA CHEMBL1741171 | EC50 | 6.7 | 6.7 | 199.0 | 1 |
| Apoptotic protease-activating factor 1 CHEMBL1795093 | IC50 | 6.0 | 6.0 | 1010.0 | 1 |
| Tyrosyl-DNA phosphodiesterase 2 CHEMBL2169736 | IC50 | 5.88 | 5.88 | 1326.0 | 1 |
| Unchecked CHEMBL612545 | IC50 | 5.84 | 5.84 | 1440.0 | 1 |
| Unchecked CHEMBL612545 | EC50 | 5.63 | 5.58 | 2336.0 | 2 |
| Heat shock protein HSP 90-alpha CHEMBL3880 | IC50 | 5.49 | 5.49 | 3214.0 | 1 |
| Hexokinase HKDC1 CHEMBL1741200 | IC50 | 5.36 | 5.07 | 4410.0 | 2 |
| Cysteine protease ATG4B CHEMBL1741221 | IC50 | 5.35 | 5.35 | 4450.0 | 1 |
| 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 CHEMBL3964 | IC50 | 4.86 | 4.86 | 13673.0 | 1 |
| Phospholipase A2 CHEMBL4426 | IC50 | 4.18 | 4.18 | 65600.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine