Compound Detail
CHEMBL1444349
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL1444349 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | JGDJMOXCCPDWPN-LZCJLJQNSA-N |
8
Targets
8
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
293.3
MW (Da)
0.67
ALogP
6
HBA
2
HBD
102.7
PSA (Ų)
0.36
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 7 meas. best 5.42
EC50 1 meas. best 4.42
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| DNA (cytosine-5)-methyltransferase 1 CHEMBL1993 | IC50 | 5.42 | 5.42 | 3850.0 | 1 |
| Sentrin-specific protease 8 CHEMBL1741207 | IC50 | 5.04 | 5.04 | 9010.0 | 1 |
| Apoptotic protease-activating factor 1 CHEMBL1795093 | IC50 | 4.89 | 4.89 | 12900.0 | 1 |
| Sentrin-specific protease 6 CHEMBL1741215 | IC50 | 4.85 | 4.85 | 14100.0 | 1 |
| Sentrin-specific protease 7 CHEMBL1741213 | IC50 | 4.59 | 4.59 | 25400.0 | 1 |
| Caspase-3 CHEMBL2334 | IC50 | 4.56 | 4.56 | 27600.0 | 1 |
| Hexokinase-1 CHEMBL2688 | EC50 | 4.42 | 4.42 | 37900.0 | 1 |
| Unchecked CHEMBL612545 | IC50 | 4.35 | 4.35 | 44300.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine