Compound Detail
CHEMBL1501508
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL1501508 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UDBULEMYJGHWPM-UHFFFAOYSA-N |
5
Targets
7
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
427.5
MW (Da)
5.72
ALogP
5
HBA
0
HBD
49.2
PSA (Ų)
0.36
QED
1
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 7 meas. best 5.96
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Zinc finger protein mex-5 CHEMBL1293319 | EC50 | 5.96 | 5.96 | 1096.0 | 1 |
| RNA-binding protein pos-1 CHEMBL1293304 | EC50 | 5.66 | 5.66 | 2197.0 | 1 |
| Neurotensin receptor type 1 CHEMBL4123 | EC50 | 5.62 | 5.62 | 2400.0 | 1 |
| BJ CHEMBL614358 | EC50 | 5.31 | 5.12 | 4860.0 | 3 |
| Unchecked CHEMBL612545 | EC50 | 4.98 | 4.98 | 10377.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Zinc finger protein mex-5 | EC50 | = | 1096.0 | nM | 5.96 | PUBCHEM_BIOASSAY: Fluorescent Polarization Homogeneous Dose Response HTS to Iden... | - |
| RNA-binding protein pos-1 | EC50 | = | 2197.0 | nM | 5.66 | PUBCHEM_BIOASSAY: Fluorescent Polarization Homogeneous Dose Response HTS to Iden... | - |
| Neurotensin receptor type 1 | EC50 | = | 2400.0 | nM | 5.62 | PUBCHEM_BIOASSAY: Dose Response confirmation of Image-Based HTS for Selective Ag... | - |
| BJ | EC50 | = | 4860.0 | nM | 5.31 | PUBCHEM_BIOASSAY: Luminescence Cell-Based Dose Response HTS to Identify Compound... | - |
| BJ | EC50 | = | 5159.0 | nM | 5.29 | PUBCHEM_BIOASSAY: Luminescence Cell-Based Dose Response HTS to Identify Compound... | - |
| Unchecked | EC50 | = | 10377.0 | nM | 4.98 | PUBCHEM_BIOASSAY: Luminescence Cell-Based Dose Response HTS to Identify Compound... | - |
| BJ | EC50 | = | 17301.0 | nM | 4.76 | PUBCHEM_BIOASSAY: Luminescence Cell-Based Dose Confirmation HTS to Identify Comp... | - |
Data from ChEMBL 36 via Core Engine