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Compound Detail

CHEMBL1533835

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O=C(c1ccc(F)cc1)c1cc2ccc(O)cc2oc1=O

Basic Information

ChEMBL ID CHEMBL1533835
Phase Preclinical
Structure Type MOL
InChI Key XXIFMDZHVXHDBW-UHFFFAOYSA-N
5
Targets
5
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

284.2
MW (Da)
2.87
ALogP
4
HBA
1
HBD
67.5
PSA (Ų)
0.58
QED
0
Ro5 Violations
2
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C16H9FO4
MW 284.24
Aromatic Rings 3
Heavy Atoms 21
NP-Likeness -0.24

Activity Summary

EC50 5 meas. best 6.34

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Unchecked
CHEMBL612545
EC50 6.34 6.34 457.0 1
Luciferin 4-monooxygenase
CHEMBL5567
EC50 6.14 6.14 731.0 1
Streptokinase A
CHEMBL1293228
EC50 5.14 5.14 7307.0 1
Streptococcus sp. 'group A'
CHEMBL612389
EC50 4.97 4.97 10697.0 1
Streptococcus
CHEMBL612313
EC50 4.8 4.8 15734.0 1

Activity Data Samples

Top measurements by pChEMBL value

Data from ChEMBL 36 via Core Engine