Compound Detail
CHEMBL1968103
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Basic Information
| ChEMBL ID | CHEMBL1968103 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DKDZXPOLPBFKGD-UHFFFAOYSA-N |
6
Targets
6
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
306.3
MW (Da)
0.61
ALogP
5
HBA
3
HBD
112.3
PSA (Ų)
0.75
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 6 meas. best 5.7
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Megakaryocyte-associated tyrosine-protein kinase CHEMBL4175 | Ki | 5.7 | 5.7 | 1995.3 | 1 |
| Ribosomal protein S6 kinase beta-1 CHEMBL4501 | Ki | 5.7 | 5.7 | 1995.3 | 1 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1A CHEMBL2292 | Ki | 5.5 | 5.5 | 3162.3 | 1 |
| Serine/threonine-protein kinase pim-3 CHEMBL5407 | Ki | 5.3 | 5.3 | 5011.9 | 1 |
| Aurora kinase B CHEMBL2185 | Ki | 5.2 | 5.2 | 6309.6 | 1 |
| MAP kinase-activated protein kinase 3 CHEMBL4670 | Ki | 5.1 | 5.1 | 7943.3 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Megakaryocyte-associated tyrosine-protein kinase | Ki | = | 1995.26 | nM | 5.7 | PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member na... | - |
| Ribosomal protein S6 kinase beta-1 | Ki | = | 1995.26 | nM | 5.7 | PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member na... | - |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1A | Ki | = | 3162.28 | nM | 5.5 | PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member na... | - |
| Serine/threonine-protein kinase pim-3 | Ki | = | 5011.87 | nM | 5.3 | PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member na... | - |
| Aurora kinase B | Ki | = | 6309.57 | nM | 5.2 | PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member na... | - |
| MAP kinase-activated protein kinase 3 | Ki | = | 7943.28 | nM | 5.1 | PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member na... | - |
Data from ChEMBL 36 via Core Engine