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Assay Detail

CHEMBL1963696

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: PHKG2
ChEMBL ↗
587
Total Activities
578
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Category other
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Phosphorylase b kinase gamma catalytic chain, liver/testis isoform (CHEMBL2349) ↗
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

PubChem BioAssay data set

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 587 5.93 8.10

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL509032 TAE-684 — 1 8.10
CHEMBL2001751 — — 1 7.90
CHEMBL1990885 — — 1 7.80
CHEMBL1993661 — — 1 7.30
CHEMBL1987034 — — 1 7.10
CHEMBL1966628 — — 1 7.00
CHEMBL592030 — — 1 6.90
CHEMBL1995813 — — 1 6.80
CHEMBL1997129 — — 1 6.80
CHEMBL1973540 — — 1 6.80
CHEMBL1986943 — — 2 6.70
CHEMBL1982957 — — 1 6.70
CHEMBL2000393 — — 1 6.60
CHEMBL1999931 — — 1 6.60
CHEMBL1992634 — — 1 6.60
CHEMBL1974328 — — 1 6.60
CHEMBL1983111 — — 1 6.60
CHEMBL210887 — — 1 6.60
CHEMBL458997 — — 1 6.50
CHEMBL1991078 — — 1 6.50
CHEMBL2000354 — — 1 6.50
CHEMBL1082440 — — 1 6.50
CHEMBL2000345 — — 1 6.50
CHEMBL2005886 — — 1 6.40
CHEMBL2000832 — — 1 6.40
CHEMBL1975500 — — 1 6.40
CHEMBL482967 CYC-116 1.0 1 6.40
CHEMBL1969301 — — 1 6.40
CHEMBL1988537 — — 1 6.30
CHEMBL2001239 — — 1 6.30

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL509032 TAE-684 Ki = 7.943 nM 8.10
CHEMBL2001751 — Ki = 12.59 nM 7.90
CHEMBL1990885 — Ki = 15.85 nM 7.80
CHEMBL1993661 — Ki = 50.12 nM 7.30
CHEMBL1987034 — Ki = 79.43 nM 7.10
CHEMBL1966628 — Ki = 100.0 nM 7.00
CHEMBL592030 — Ki = 125.89 nM 6.90
CHEMBL1995813 — Ki = 158.49 nM 6.80
CHEMBL1997129 — Ki = 158.49 nM 6.80
CHEMBL1973540 — Ki = 158.49 nM 6.80
CHEMBL1986943 — Ki = 199.53 nM 6.70
CHEMBL1986943 — Ki = 199.53 nM 6.70
CHEMBL1982957 — Ki = 199.53 nM 6.70
CHEMBL1974328 — Ki = 251.19 nM 6.60
CHEMBL1992634 — Ki = 251.19 nM 6.60
CHEMBL2000393 — Ki = 251.19 nM 6.60
CHEMBL1999931 — Ki = 251.19 nM 6.60
CHEMBL1983111 — Ki = 251.19 nM 6.60
CHEMBL210887 — Ki = 251.19 nM 6.60
CHEMBL1991078 — Ki = 316.23 nM 6.50
CHEMBL2000345 — Ki = 316.23 nM 6.50
CHEMBL458997 — Ki = 316.23 nM 6.50
CHEMBL2000354 — Ki = 316.23 nM 6.50
CHEMBL1082440 — Ki = 316.23 nM 6.50
CHEMBL1975500 — Ki = 398.11 nM 6.40
CHEMBL2005886 — Ki = 398.11 nM 6.40
CHEMBL1969301 — Ki = 398.11 nM 6.40
CHEMBL2000832 — Ki = 398.11 nM 6.40
CHEMBL482967 CYC-116 Ki = 398.11 nM 6.40
CHEMBL2001239 — Ki = 501.19 nM 6.30
CHEMBL1988537 — Ki = 501.19 nM 6.30
CHEMBL1968705 — Ki = 630.96 nM 6.20
CHEMBL1968380 — Ki = 630.96 nM 6.20
CHEMBL1725279 SP-600125 Ki = 630.96 nM 6.20
CHEMBL1998121 — Ki = 794.33 nM 6.10
CHEMBL1974870 — Ki = 794.33 nM 6.10
CHEMBL1981047 — Ki = 794.33 nM 6.10
CHEMBL2002649 — Ki = 794.33 nM 6.10
CHEMBL1988173 — Ki = 794.33 nM 6.10
CHEMBL1982711 — Ki = 794.33 nM 6.10
CHEMBL1970522 — Ki = 794.33 nM 6.10
CHEMBL1190711 — Ki = 1000.0 nM 6.00
CHEMBL249282 — Ki = 1000.0 nM 6.00
CHEMBL1970903 — Ki = 1000.0 nM 6.00
CHEMBL522892 DOVITINIB Ki = 1000.0 nM 6.00
CHEMBL2002702 — Ki = 1000.0 nM 6.00
CHEMBL1966425 — Ki = 1000.0 nM 6.00
CHEMBL1991063 — Ki = 1000.0 nM 6.00
CHEMBL1990482 — Ki = 1000.0 nM 6.00
CHEMBL2002726 — Ki = 1000.0 nM 6.00