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Assay Detail

CHEMBL1963716

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: STK22B
ChEMBL ↗
512
Total Activities
507
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Category other
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Testis-specific serine/threonine-protein kinase 2 (CHEMBL6014) ↗
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

PubChem BioAssay data set

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 512 6.40 8.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1971029 — — 1 8.00
CHEMBL509032 TAE-684 — 1 8.00
CHEMBL1978448 — — 1 7.40
CHEMBL514499 GW843682X — 1 7.20
CHEMBL1998159 — — 1 7.10
CHEMBL1991078 — — 1 7.10
CHEMBL1974328 — — 1 7.10
CHEMBL1993661 — — 1 7.00
CHEMBL1995813 — — 1 7.00
CHEMBL539474 — — 1 6.80
CHEMBL1969523 — — 1 6.80
CHEMBL1987034 — — 1 6.70
CHEMBL1983111 — — 1 6.60
CHEMBL1967878 CENISERTIB 2.0 1 6.60
CHEMBL2006263 — — 1 6.50
CHEMBL1997129 — — 1 6.30
CHEMBL2001239 — — 1 6.30
CHEMBL1975138 — — 1 6.30
CHEMBL1990885 — — 1 6.20
CHEMBL1825138 — — 1 6.20
CHEMBL1966628 — — 1 6.10
CHEMBL2000832 — — 1 6.10
CHEMBL2004544 — — 1 6.10
CHEMBL1241473 — — 1 6.10
CHEMBL1997349 — — 1 6.10
CHEMBL2001751 — — 1 6.10
CHEMBL50894 ALSTERPAULLONE — 1 6.00
CHEMBL526133 — — 1 6.00
CHEMBL1980391 RG-1530 1.0 1 6.00
CHEMBL519697 — — 1 5.90

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1971029 — Ki = 10.0 nM 8.00
CHEMBL509032 TAE-684 Ki = 10.0 nM 8.00
CHEMBL1978448 — Ki = 39.81 nM 7.40
CHEMBL514499 GW843682X Ki = 63.1 nM 7.20
CHEMBL1998159 — Ki = 79.43 nM 7.10
CHEMBL1974328 — Ki = 79.43 nM 7.10
CHEMBL1991078 — Ki = 79.43 nM 7.10
CHEMBL1993661 — Ki = 100.0 nM 7.00
CHEMBL1995813 — Ki = 100.0 nM 7.00
CHEMBL1969523 — Ki = 158.49 nM 6.80
CHEMBL539474 — Ki = 158.49 nM 6.80
CHEMBL1987034 — Ki = 199.53 nM 6.70
CHEMBL1983111 — Ki = 251.19 nM 6.60
CHEMBL1967878 CENISERTIB Ki = 251.19 nM 6.60
CHEMBL2006263 — Ki = 316.23 nM 6.50
CHEMBL2001239 — Ki = 501.19 nM 6.30
CHEMBL1975138 — Ki = 501.19 nM 6.30
CHEMBL1997129 — Ki = 501.19 nM 6.30
CHEMBL1990885 — Ki = 630.96 nM 6.20
CHEMBL1825138 — Ki = 630.96 nM 6.20
CHEMBL2000832 — Ki = 794.33 nM 6.10
CHEMBL2004544 — Ki = 794.33 nM 6.10
CHEMBL1241473 — Ki = 794.33 nM 6.10
CHEMBL2001751 — Ki = 794.33 nM 6.10
CHEMBL1997349 — Ki = 794.33 nM 6.10
CHEMBL1966628 — Ki = 794.33 nM 6.10
CHEMBL1980391 RG-1530 Ki = 1000.0 nM 6.00
CHEMBL526133 — Ki = 1000.0 nM 6.00
CHEMBL50894 ALSTERPAULLONE Ki = 1000.0 nM 6.00
CHEMBL1992922 — Ki = 1258.93 nM 5.90
CHEMBL1989805 — Ki = 1258.93 nM 5.90
CHEMBL519697 — Ki = 1258.93 nM 5.90
CHEMBL2000354 — Ki = 1258.93 nM 5.90
CHEMBL1995740 — Ki = 1258.93 nM 5.90
CHEMBL1969588 — Ki = 1258.93 nM 5.90
CHEMBL583144 — Ki = 1258.93 nM 5.90
CHEMBL1964687 — Ki = 1258.93 nM 5.90
CHEMBL1974870 — Ki = 1584.89 nM 5.80
CHEMBL1988838 — Ki = 1584.89 nM 5.80
CHEMBL592030 — Ki = 1584.89 nM 5.80
CHEMBL1975233 — Ki = 1584.89 nM 5.80
CHEMBL10 SB-203580 Ki > 1584.89 nM -
CHEMBL1682552 — Ki > 1584.89 nM -
CHEMBL1964937 — Ki > 1584.89 nM -
CHEMBL1980163 — Ki > 1584.89 nM -
CHEMBL1969506 — Ki > 1584.89 nM -
CHEMBL2005899 — Ki > 1584.89 nM -
CHEMBL1242373 — Ki > 1584.89 nM -
CHEMBL1986781 — Ki > 1584.89 nM -
CHEMBL1974935 — Ki > 1584.89 nM -