Compound Detail
CHEMBL1376540
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Basic Information
| ChEMBL ID | CHEMBL1376540 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | TVSOMCJVQKDEQZ-UHFFFAOYSA-N |
8
Targets
9
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
309.3
MW (Da)
1.80
ALogP
4
HBA
2
HBD
83.5
PSA (Ų)
0.65
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 8 meas. best 6.06
EC50 1 meas. best 4.8
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| SUMO-activating enzyme CHEMBL2095174 | IC50 | 6.06 | 5.65 | 870.0 | 2 |
| Sentrin-specific protease 6 CHEMBL1741215 | IC50 | 5.46 | 5.46 | 3480.0 | 1 |
| Sentrin-specific protease 7 CHEMBL1741213 | IC50 | 5.36 | 5.36 | 4400.0 | 1 |
| Sentrin-specific protease 8 CHEMBL1741207 | IC50 | 5.31 | 5.31 | 4890.0 | 1 |
| Apoptotic protease-activating factor 1 CHEMBL1795093 | IC50 | 5.29 | 5.29 | 5130.0 | 1 |
| Tyrosyl-DNA phosphodiesterase 2 CHEMBL2169736 | IC50 | 5.24 | 5.24 | 5743.0 | 1 |
| Unchecked CHEMBL612545 | IC50 | 5.11 | 5.11 | 7710.0 | 1 |
| Protein RecA CHEMBL1741171 | EC50 | 4.8 | 4.8 | 15900.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine