Compound Detail
CHEMBL14047
PHENYLGUANIDINE Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL14047 |
| Name | PHENYLGUANIDINE |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | QRJZGVVKGFIGLI-UHFFFAOYSA-N |
6
Targets
14
Activities
2
Assay Types
0
PK Parameters
20
Publications
0
Known Names
Molecular Properties
135.2
MW (Da)
0.99
ALogP
1
HBA
3
HBD
61.9
PSA (Ų)
0.40
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 8 meas. best 5.63
IC50 6 meas. best 4.7
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Serotonin 3 (5-HT3) receptor CHEMBL2094132 | Ki | 5.63 | 5.63 | 2340.0 | 2 |
| Urokinase-type plasminogen activator CHEMBL3286 | IC50 | 4.7 | 4.7 | 20000.0 | 1 |
| Urokinase-type plasminogen activator CHEMBL3286 | Ki | 4.69 | 4.69 | 20600.0 | 2 |
| Solute carrier family 22 member 1 CHEMBL5685 | IC50 | 4.39 | 4.39 | 41100.0 | 1 |
| Amine oxidase [copper-containing] 3 CHEMBL4592 | IC50 | 4.11 | 4.11 | 78000.0 | 1 |
| Solute carrier family 22 member 2 CHEMBL1743122 | IC50 | 4.05 | 4.05 | 89000.0 | 1 |
| Solute carrier family 22 member 3 CHEMBL2073673 | IC50 | 4.0 | 4.0 | 99800.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Literature References
Data from ChEMBL 36 via Core Engine