Compound Detail
CHEMBL1415156
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Basic Information
| ChEMBL ID | CHEMBL1415156 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | NGFYSVJWYNOJNU-UHFFFAOYSA-N |
11
Targets
11
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
458.3
MW (Da)
5.05
ALogP
6
HBA
1
HBD
96.7
PSA (Ų)
0.41
QED
1
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 11 meas. best 5.69
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Sentrin-specific protease 6 CHEMBL1741215 | IC50 | 5.69 | 5.69 | 2030.0 | 1 |
| Plectin CHEMBL1293240 | IC50 | 5.43 | 5.43 | 3734.3 | 1 |
| Sentrin-specific protease 7 CHEMBL1741213 | IC50 | 5.43 | 5.43 | 3690.0 | 1 |
| Sentrin-specific protease 8 CHEMBL1741207 | IC50 | 5.34 | 5.34 | 4550.0 | 1 |
| Peroxisome proliferator-activated receptor gamma/Nuclear receptor corepressor 2 CHEMBL2096976 | IC50 | 5.29 | 5.29 | 5079.0 | 1 |
| Unchecked CHEMBL612545 | IC50 | 5.21 | 5.21 | 6240.0 | 1 |
| Apoptotic protease-activating factor 1 CHEMBL1795093 | IC50 | 5.14 | 5.14 | 7220.0 | 1 |
| Aminopeptidase N CHEMBL4117 | IC50 | 4.64 | 4.64 | 22900.0 | 1 |
| Tyrosyl-DNA phosphodiesterase 2 CHEMBL2169736 | IC50 | 4.54 | 4.54 | 29094.0 | 1 |
| Caspase-3 CHEMBL2334 | IC50 | 4.53 | 4.53 | 29600.0 | 1 |
| Dual specificity protein phosphatase 6 CHEMBL5511 | IC50 | 4.01 | 4.01 | 96900.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine