Compound Detail
CHEMBL1449334
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Basic Information
| ChEMBL ID | CHEMBL1449334 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | SERAYZIPJKSYSO-UHFFFAOYSA-N |
7
Targets
11
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
259.3
MW (Da)
3.11
ALogP
6
HBA
0
HBD
65.0
PSA (Ų)
0.67
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 11 meas. best 5.98
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Tyrosine-protein phosphatase non-receptor type 7 CHEMBL2219 | IC50 | 5.98 | 5.18 | 1040.0 | 2 |
| SUMO-activating enzyme CHEMBL2095174 | IC50 | 5.54 | 5.18 | 2910.0 | 2 |
| Induced myeloid leukemia cell differentiation protein Mcl-1 CHEMBL4361 | IC50 | 5.1 | 4.99 | 8015.8 | 2 |
| Nuclear receptor subfamily 4immunitygroup A member 1 CHEMBL1293229 | IC50 | 4.71 | 4.71 | 19357.0 | 1 |
| Dual specificity protein phosphatase 3 CHEMBL2635 | IC50 | 4.53 | 4.53 | 29500.0 | 1 |
| Dual specificity protein phosphatase 6 CHEMBL5511 | IC50 | 4.09 | 4.045 | 80400.0 | 2 |
| Glyceraldehyde-3-phosphate dehydrogenase CHEMBL2284 | IC50 | 4.0 | 4.0 | 99100.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine