Compound Detail
CHEMBL1988331
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL1988331 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | PWIKZIKRKUUHRB-UHFFFAOYSA-N |
9
Targets
9
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
362.9
MW (Da)
5.51
ALogP
3
HBA
2
HBD
53.6
PSA (Ų)
0.47
QED
1
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 9 meas. best 8.9
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Cell division cycle 7-related protein kinase CHEMBL5443 | Ki | 8.9 | 8.9 | 1.3 | 1 |
| Mitogen-activated protein kinase kinase kinase kinase 4 CHEMBL6166 | Ki | 8.4 | 8.4 | 4.0 | 1 |
| Dual specificity protein kinase CLK4 CHEMBL4203 | Ki | 8.3 | 8.3 | 5.0 | 1 |
| Glycogen synthase kinase-3 beta CHEMBL262 | Ki | 7.6 | 7.6 | 25.1 | 1 |
| Rho-associated protein kinase 2 CHEMBL2973 | Ki | 7.5 | 7.5 | 31.6 | 1 |
| cAMP-dependent protein kinase catalytic subunit alpha CHEMBL4101 | Ki | 6.8 | 6.8 | 158.5 | 1 |
| Cyclin-dependent kinase 2 CHEMBL301 | Ki | 6.7 | 6.7 | 199.5 | 1 |
| Homeodomain-interacting protein kinase 2 CHEMBL4576 | Ki | 6.4 | 6.4 | 398.1 | 1 |
| Serine/threonine-protein kinase pim-1 CHEMBL2147 | Ki | 6.3 | 6.3 | 501.2 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine