Compound Detail
CHEMBL1999774
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Basic Information
| ChEMBL ID | CHEMBL1999774 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ZMEIPDPKFPZUIJ-UHFFFAOYSA-N |
9
Targets
9
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
336.8
MW (Da)
1.37
ALogP
5
HBA
3
HBD
112.3
PSA (Ų)
0.78
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 9 meas. best 6.9
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Serine/threonine-protein kinase pim-1 CHEMBL2147 | Ki | 6.9 | 6.9 | 125.9 | 1 |
| Serine/threonine-protein kinase pim-2 CHEMBL4523 | Ki | 5.9 | 5.9 | 1258.9 | 1 |
| Vascular endothelial growth factor receptor 3 CHEMBL1955 | Ki | 5.5 | 5.5 | 3162.3 | 1 |
| Serine/threonine-protein kinase D2 CHEMBL4900 | Ki | 5.4 | 5.4 | 3981.1 | 1 |
| Casein kinase II subunit alpha CHEMBL3629 | Ki | 5.2 | 5.2 | 6309.6 | 1 |
| Protein kinase C delta type CHEMBL2996 | Ki | 5.1 | 5.1 | 7943.3 | 1 |
| Cyclin-dependent kinase 2 CHEMBL301 | Ki | 5.1 | 5.1 | 7943.3 | 1 |
| Serine/threonine-protein kinase PAK 1 CHEMBL4600 | Ki | 5.0 | 5.0 | 10000.0 | 1 |
| MAP kinase-activated protein kinase 3 CHEMBL4670 | Ki | 5.0 | 5.0 | 10000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine