Compound Detail
CHEMBL3891892
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
COc1cc(OC)cc(N(CCCNC(=O)C(F)(F)F)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1
Basic Information
| ChEMBL ID | CHEMBL3891892 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FFFJXBUHHHYLPP-UHFFFAOYSA-N |
5
Targets
8
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
514.5
MW (Da)
4.25
ALogP
8
HBA
1
HBD
94.4
PSA (Ų)
0.33
QED
1
Ro5 Violations
9
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 8 meas. best 8.97
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Fibroblast growth factor receptor 3 CHEMBL2742 | IC50 | 8.97 | 8.26 | 1.1 | 2 |
| Fibroblast growth factor receptor 1 CHEMBL3650 | IC50 | 8.96 | 7.805 | 1.1 | 2 |
| Fibroblast growth factor receptor 4 CHEMBL3973 | IC50 | 8.58 | 8.58 | 2.6 | 1 |
| Fibroblast growth factor receptor 2 CHEMBL4142 | IC50 | 8.45 | 8.45 | 3.5 | 1 |
| Vascular endothelial growth factor receptor 2 CHEMBL279 | IC50 | 7.64 | 6.715 | 22.9 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine