Compound Detail
CHEMBL3944320
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CCN(CCN(c1cc(OC)cc(OC)c1)c1ccc2ncc(-c3cnn(C)c3)nc2c1)C(C)C.Cl
Basic Information
| ChEMBL ID | CHEMBL3944320 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | VISMWVZBCCXDPW-UHFFFAOYSA-N |
| Parent Compound | CHEMBL3991072 |
| Active Moiety | CHEMBL3991072 |
5
Targets
8
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
474.6
MW (Da)
4.92
ALogP
8
HBA
0
HBD
68.5
PSA (Ų)
0.32
QED
0
Ro5 Violations
10
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 8 meas. best 8.66
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Fibroblast growth factor receptor 2 CHEMBL4142 | IC50 | 8.66 | 8.66 | 2.2 | 1 |
| Fibroblast growth factor receptor 1 CHEMBL3650 | IC50 | 8.63 | 8.02 | 2.3 | 2 |
| Fibroblast growth factor receptor 3 CHEMBL2742 | IC50 | 8.46 | 8.1 | 3.5 | 2 |
| Fibroblast growth factor receptor 4 CHEMBL3973 | IC50 | 7.92 | 7.92 | 12.0 | 1 |
| Vascular endothelial growth factor receptor 2 CHEMBL279 | IC50 | 7.1 | 6.63 | 79.4 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine