Compound Detail
CHEMBL3983996
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
COc1cc(OC)cc(N(CCN2CCC(N)C2)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1.Cl
Basic Information
| ChEMBL ID | CHEMBL3983996 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | NWZKUZJBZXCSMZ-UHFFFAOYSA-N |
| Parent Compound | CHEMBL3990769 |
| Active Moiety | CHEMBL3990769 |
5
Targets
8
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
473.6
MW (Da)
3.22
ALogP
9
HBA
1
HBD
94.6
PSA (Ų)
0.42
QED
0
Ro5 Violations
8
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 8 meas. best 8.85
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Fibroblast growth factor receptor 1 CHEMBL3650 | IC50 | 8.85 | 7.725 | 1.4 | 2 |
| Fibroblast growth factor receptor 2 CHEMBL4142 | IC50 | 8.7 | 8.7 | 2.0 | 1 |
| Fibroblast growth factor receptor 3 CHEMBL2742 | IC50 | 8.68 | 7.8 | 2.1 | 2 |
| Fibroblast growth factor receptor 4 CHEMBL3973 | IC50 | 7.99 | 7.99 | 10.2 | 1 |
| Vascular endothelial growth factor receptor 2 CHEMBL279 | IC50 | 7.72 | 6.765 | 19.1 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine