Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL1963759

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: INSR
ChEMBL ↗
738
Total Activities
725
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Category other
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Insulin receptor (CHEMBL1981) ↗
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

PubChem BioAssay data set

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 738 6.30 8.60

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1981725 — — 1 8.60
CHEMBL2000271 — — 1 8.60
CHEMBL458997 — — 1 8.30
CHEMBL1996234 — — 1 8.20
CHEMBL1241473 — — 1 8.20
CHEMBL1980995 — — 1 7.90
CHEMBL1968791 — — 1 7.80
CHEMBL2005886 — — 1 7.60
CHEMBL1977148 — — 1 7.60
CHEMBL1989708 — — 2 7.60
CHEMBL1983111 — — 1 7.60
CHEMBL1984711 — — 1 7.40
CHEMBL1090356 — — 1 7.40
CHEMBL1090360 — — 1 7.40
CHEMBL1988370 — — 1 7.40
CHEMBL1991429 — — 1 7.40
CHEMBL1987034 — — 1 7.40
CHEMBL2004290 — — 1 7.30
CHEMBL1967116 — — 1 7.20
CHEMBL1993661 — — 1 7.20
CHEMBL1991138 — — 1 7.10
CHEMBL244378 — — 1 7.00
CHEMBL1984162 — — 1 7.00
CHEMBL1987054 — — 1 7.00
CHEMBL1980297 ILORASERTIB 2.0 1 7.00
CHEMBL1993941 — — 1 6.90
CHEMBL1988163 — — 1 6.90
CHEMBL2002165 — — 1 6.90
CHEMBL1965910 — — 1 6.90
CHEMBL1970317 — — 1 6.90

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2000271 — Ki = 2.512 nM 8.60
CHEMBL1981725 — Ki = 2.512 nM 8.60
CHEMBL458997 — Ki = 5.012 nM 8.30
CHEMBL1996234 — Ki = 6.31 nM 8.20
CHEMBL1241473 — Ki = 6.31 nM 8.20
CHEMBL1980995 — Ki = 12.59 nM 7.90
CHEMBL1968791 — Ki = 15.85 nM 7.80
CHEMBL2005886 — Ki = 25.12 nM 7.60
CHEMBL1989708 — Ki = 25.12 nM 7.60
CHEMBL1977148 — Ki = 25.12 nM 7.60
CHEMBL1983111 — Ki = 25.12 nM 7.60
CHEMBL1987034 — Ki = 39.81 nM 7.40
CHEMBL1991429 — Ki = 39.81 nM 7.40
CHEMBL1090356 — Ki = 39.81 nM 7.40
CHEMBL1090360 — Ki = 39.81 nM 7.40
CHEMBL1984711 — Ki = 39.81 nM 7.40
CHEMBL1988370 — Ki = 39.81 nM 7.40
CHEMBL2004290 — Ki = 50.12 nM 7.30
CHEMBL1993661 — Ki = 63.1 nM 7.20
CHEMBL1967116 — Ki = 63.1 nM 7.20
CHEMBL1989708 — Ki = 79.43 nM 7.10
CHEMBL1991138 — Ki = 79.43 nM 7.10
CHEMBL1987054 — Ki = 100.0 nM 7.00
CHEMBL1984162 — Ki = 100.0 nM 7.00
CHEMBL1980297 ILORASERTIB Ki = 100.0 nM 7.00
CHEMBL244378 — Ki = 100.0 nM 7.00
CHEMBL1993941 — Ki = 125.89 nM 6.90
CHEMBL2002165 — Ki = 125.89 nM 6.90
CHEMBL1967878 CENISERTIB Ki = 125.89 nM 6.90
CHEMBL1970317 — Ki = 125.89 nM 6.90
CHEMBL1988163 — Ki = 125.89 nM 6.90
CHEMBL1965910 — Ki = 125.89 nM 6.90
CHEMBL385478 — Ki = 158.49 nM 6.80
CHEMBL1988387 — Ki = 158.49 nM 6.80
CHEMBL2002702 — Ki = 158.49 nM 6.80
CHEMBL1969102 — Ki = 158.49 nM 6.80
CHEMBL1990885 — Ki = 199.53 nM 6.70
CHEMBL2004716 — Ki = 199.53 nM 6.70
CHEMBL1982476 — Ki = 199.53 nM 6.70
CHEMBL1988838 — Ki = 199.53 nM 6.70
CHEMBL1967720 — Ki = 199.53 nM 6.70
CHEMBL2007151 — Ki = 199.53 nM 6.70
CHEMBL1997617 — Ki = 251.19 nM 6.60
CHEMBL1977041 — Ki = 251.19 nM 6.60
CHEMBL1972584 — Ki = 251.19 nM 6.60
CHEMBL1972584 — Ki = 251.19 nM 6.60
CHEMBL396523 — Ki = 316.23 nM 6.50
CHEMBL1979516 — Ki = 316.23 nM 6.50
CHEMBL1974254 — Ki = 316.23 nM 6.50
CHEMBL2006715 — Ki = 316.23 nM 6.50