| Tyrosine-protein kinase Lck CHEMBL258 | Ki | 8.1 | 8.1 | 7.9 | 1 |
| Tyrosine-protein kinase Fyn CHEMBL1841 | Ki | 7.8 | 7.8 | 15.8 | 1 |
| Macrophage colony-stimulating factor 1 receptor CHEMBL1844 | Ki | 7.6 | 7.6 | 25.1 | 1 |
| Insulin receptor CHEMBL1981 | Ki | 7.4 | 7.4 | 39.8 | 1 |
| Protein-tyrosine kinase 2-beta CHEMBL5469 | Ki | 7.4 | 7.4 | 39.8 | 1 |
| Mitogen-activated protein kinase 8 CHEMBL2276 | Ki | 7.3 | 7.3 | 50.1 | 1 |
| Proto-oncogene tyrosine-protein kinase Src CHEMBL267 | Ki | 7.3 | 7.3 | 50.1 | 1 |
| Vascular endothelial growth factor receptor 2 CHEMBL279 | Ki | 7.2 | 7.2 | 63.1 | 1 |
| Tyrosine-protein kinase Blk CHEMBL2250 | Ki | 7.1 | 7.1 | 79.4 | 1 |
| Tyrosine-protein kinase Lyn CHEMBL3905 | Ki | 7.1 | 7.1 | 79.4 | 1 |
| Focal adhesion kinase 1 CHEMBL2695 | Ki | 7.0 | 7.0 | 100.0 | 1 |
| Ephrin type-A receptor 2 CHEMBL2068 | Ki | 6.9 | 6.9 | 125.9 | 1 |
| Tyrosine-protein kinase ITK/TSK CHEMBL2959 | Ki | 6.8 | 6.8 | 158.5 | 1 |
| Receptor-type tyrosine-protein kinase FLT3 CHEMBL1974 | Ki | 6.7 | 6.7 | 199.5 | 1 |
| Insulin-like growth factor 1 receptor CHEMBL1957 | Ki | 6.7 | 6.7 | 199.5 | 1 |
| Vascular endothelial growth factor receptor 1 CHEMBL1868 | Ki | 6.7 | 6.7 | 199.5 | 1 |
| Epidermal growth factor receptor CHEMBL203 | Ki | 6.4 | 6.4 | 398.1 | 1 |
| Serine/threonine-protein kinase PLK4 CHEMBL3788 | Ki | 6.4 | 6.4 | 398.1 | 1 |
| Tyrosine-protein kinase JAK2 CHEMBL2971 | Ki | 6.4 | 6.4 | 398.1 | 1 |
| Mitogen-activated protein kinase 9 CHEMBL4179 | Ki | 6.3 | 6.3 | 501.2 | 1 |
| STE20-like serine/threonine-protein kinase CHEMBL4202 | Ki | 6.3 | 6.3 | 501.2 | 1 |
| Aurora kinase A CHEMBL4722 | Ki | 6.2 | 6.2 | 631.0 | 1 |
| LIM domain kinase 1 CHEMBL3836 | Ki | 6.2 | 6.2 | 631.0 | 1 |
| BDNF/NT-3 growth factors receptor CHEMBL4898 | Ki | 6.0 | 6.0 | 1000.0 | 1 |
| Tyrosine-protein kinase receptor UFO CHEMBL4895 | Ki | 6.0 | 6.0 | 1000.0 | 1 |
| Serine/threonine-protein kinase PAK 4 CHEMBL4482 | Ki | 6.0 | 6.0 | 1000.0 | 1 |
| Interleukin-1 receptor-associated kinase 1 CHEMBL3357 | Ki | 5.9 | 5.9 | 1258.9 | 1 |
| Glycogen synthase kinase-3 alpha CHEMBL2850 | Ki | 5.9 | 5.9 | 1258.9 | 1 |
| Aurora kinase B CHEMBL2185 | Ki | 5.9 | 5.9 | 1258.9 | 1 |
| High affinity nerve growth factor receptor CHEMBL2815 | Ki | 5.8 | 5.8 | 1584.9 | 1 |
| Dual specificity protein kinase CLK4 CHEMBL4203 | Ki | 5.7 | 5.7 | 1995.3 | 1 |
| Serine/threonine-protein kinase PLK3 CHEMBL4897 | Ki | 5.6 | 5.6 | 2511.9 | 1 |
| Serine/threonine-protein kinase TAO1 CHEMBL5261 | Ki | 5.6 | 5.6 | 2511.9 | 1 |
| Interleukin-1 receptor-associated kinase 4 CHEMBL3778 | Ki | 5.6 | 5.6 | 2511.9 | 1 |
| Glycogen synthase kinase-3 beta CHEMBL262 | Ki | 5.6 | 5.6 | 2511.9 | 1 |
| Dual specificity protein kinase CLK2 CHEMBL4225 | Ki | 5.5 | 5.5 | 3162.3 | 1 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1A CHEMBL2292 | Ki | 5.5 | 5.5 | 3162.3 | 1 |
| MAP/microtubule affinity-regulating kinase 3 CHEMBL5600 | Ki | 5.4 | 5.4 | 3981.1 | 1 |
| Mitogen-activated protein kinase 12 CHEMBL4674 | Ki | 5.4 | 5.4 | 3981.1 | 1 |
| Serine/threonine-protein kinase MARK2 CHEMBL3831 | Ki | 5.4 | 5.4 | 3981.1 | 1 |
| Mitogen-activated protein kinase kinase kinase 20 CHEMBL3886 | Ki | 5.4 | 5.4 | 3981.1 | 1 |
| Casein kinase II subunit alpha CHEMBL3629 | Ki | 5.4 | 5.4 | 3981.1 | 1 |
| Cyclin-dependent kinase 1 CHEMBL308 | Ki | 5.4 | 5.4 | 3981.1 | 1 |
| Fibroblast growth factor receptor 1 CHEMBL3650 | Ki | 5.3 | 5.3 | 5011.9 | 1 |
| Mitogen-activated protein kinase kinase kinase kinase 4 CHEMBL6166 | Ki | 5.3 | 5.3 | 5011.9 | 1 |
| Serine/threonine-protein kinase Nek4 CHEMBL5819 | Ki | 5.3 | 5.3 | 5011.9 | 1 |
| Mitogen-activated protein kinase kinase kinase kinase 5 CHEMBL4852 | Ki | 5.2 | 5.2 | 6309.6 | 1 |
| Serine/threonine-protein kinase PAK 1 CHEMBL4600 | Ki | 5.2 | 5.2 | 6309.6 | 1 |
| MAP kinase-interacting serine/threonine-protein kinase 2 CHEMBL4204 | Ki | 5.2 | 5.2 | 6309.6 | 1 |
| Misshapen-like kinase 1 CHEMBL5518 | Ki | 5.1 | 5.1 | 7943.3 | 1 |