Compound Detail
CHEMBL1466495
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Basic Information
| ChEMBL ID | CHEMBL1466495 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | GMXOVSWRMQJDGU-UHFFFAOYSA-N |
8
Targets
10
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
466.4
MW (Da)
5.82
ALogP
6
HBA
2
HBD
75.1
PSA (Ų)
0.34
QED
1
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 5 meas. best 5.17
IC50 5 meas. best 5.25
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Corticotropin-releasing factor receptor 2/Corticotropin-releasing factor-binding protein CHEMBL3885546 | IC50 | 5.25 | 5.25 | 5650.0 | 1 |
| Streptokinase A CHEMBL1293228 | EC50 | 5.17 | 4.77 | 6791.0 | 2 |
| HEK293 CHEMBL614818 | EC50 | 5.17 | 5.17 | 6750.0 | 1 |
| Nucleotide-binding oligomerization domain-containing protein 1 CHEMBL1293222 | IC50 | 5.13 | 5.13 | 7370.0 | 1 |
| Tumor necrosis factor CHEMBL1825 | IC50 | 5.06 | 5.06 | 8650.0 | 1 |
| Streptococcus sp. 'group A' CHEMBL612389 | EC50 | 5.04 | 5.04 | 9127.0 | 1 |
| HEK293 CHEMBL614818 | IC50 | 5.02 | 5.02 | 9467.0 | 1 |
| Nucleotide-binding oligomerization domain-containing protein 2 CHEMBL1293266 | IC50 | 5.0 | 5.0 | 9950.0 | 1 |
| Streptococcus CHEMBL612313 | EC50 | 4.42 | 4.42 | 38470.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine