Compound Detail
CHEMBL1546228
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Basic Information
| ChEMBL ID | CHEMBL1546228 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FANCAJKOSFUJAW-UHFFFAOYSA-N |
7
Targets
9
Activities
2
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
226.2
MW (Da)
1.72
ALogP
4
HBA
1
HBD
58.5
PSA (Ų)
0.62
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 8 meas. best 6.62
IC50 1 meas. best 4.9
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | EC50 | 6.62 | 6.62 | 237.0 | 1 |
| ATP-dependent molecular chaperone HSP82 CHEMBL1293251 | EC50 | 6.06 | 5.84 | 879.0 | 3 |
| Serine/threonine-protein phosphatase CHEMBL1293271 | EC50 | 5.61 | 5.61 | 2468.0 | 1 |
| Streptococcus sp. 'group A' CHEMBL612389 | EC50 | 5.54 | 5.54 | 2857.0 | 1 |
| Streptokinase A CHEMBL1293228 | EC50 | 5.45 | 5.45 | 3514.0 | 1 |
| Streptococcus CHEMBL612313 | EC50 | 5.02 | 5.02 | 9574.0 | 1 |
| NS3 CHEMBL1293269 | IC50 | 4.9 | 4.9 | 12629.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 21459001 | 10.1016/j.bmc.2011.03.012 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine