Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL1970867

Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
O=C(N/N=C/c1cc(Cl)cc([N+](=O)[O-])c1O)c1ccccc1NS(=O)(=O)c1cccs1

Basic Information

ChEMBL ID CHEMBL1970867
Phase Preclinical
Structure Type MOL
InChI Key XCUZAOJYLVPYGX-KEBDBYFISA-N
8
Targets
9
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

480.9
MW (Da)
3.58
ALogP
8
HBA
3
HBD
151.0
PSA (Ų)
0.27
QED
0
Ro5 Violations
7
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C18H13ClN4O6S2
MW 480.91
Aromatic Rings 3
Heavy Atoms 31
NP-Likeness -2.57

Activity Summary

EC50 6 meas. best 5.81
IC50 3 meas. best 4.98

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Zinc finger protein mex-5
CHEMBL1293319
EC50 5.81 5.81 1556.0 1
Streptococcus sp. 'group A'
CHEMBL612389
EC50 5.37 5.37 4306.0 1
26S proteasome non-ATPase regulatory subunit 14
CHEMBL2007629
IC50 4.98 4.98 10400.0 1
Streptokinase A
CHEMBL1293228
EC50 4.92 4.92 12049.0 1
Envelope glycoprotein gp160
CHEMBL1293311
IC50 4.87 4.87 13600.0 1
Streptococcus
CHEMBL612313
EC50 4.72 4.72 18852.0 1
Protein RecA
CHEMBL1741171
EC50 4.17 4.17 67200.0 1
Prothrombin
CHEMBL4471
IC50 4.07 4.07 85500.0 1

Activity Data Samples

Top measurements by pChEMBL value

Data from ChEMBL 36 via Core Engine