Compound Detail
CHEMBL2003420
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL2003420 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | MHRZYVYAAMLZJC-UHFFFAOYSA-N |
8
Targets
8
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
384.5
MW (Da)
2.34
ALogP
4
HBA
4
HBD
108.0
PSA (Ų)
0.45
QED
0
Ro5 Violations
11
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 8 meas. best 7.1
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| MAP/microtubule affinity-regulating kinase 3 CHEMBL5600 | Ki | 7.1 | 7.1 | 79.4 | 1 |
| Non-receptor tyrosine-protein kinase TYK2 CHEMBL3553 | Ki | 6.5 | 6.5 | 316.2 | 1 |
| Tyrosine-protein kinase SYK CHEMBL2599 | Ki | 6.3 | 6.3 | 501.2 | 1 |
| Proto-oncogene tyrosine-protein kinase receptor Ret CHEMBL2041 | Ki | 6.0 | 6.0 | 1000.0 | 1 |
| Dual specificity protein kinase CLK4 CHEMBL4203 | Ki | 5.8 | 5.8 | 1584.9 | 1 |
| Tyrosine-protein kinase Fes/Fps CHEMBL5455 | Ki | 5.7 | 5.7 | 1995.3 | 1 |
| Vascular endothelial growth factor receptor 3 CHEMBL1955 | Ki | 5.4 | 5.4 | 3981.1 | 1 |
| Dual specificity protein kinase CLK2 CHEMBL4225 | Ki | 5.1 | 5.1 | 7943.3 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine