Compound Detail
CHEMBL2004631
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Basic Information
| ChEMBL ID | CHEMBL2004631 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UOOFSEUSROQBBP-UHFFFAOYSA-N |
10
Targets
11
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
330.4
MW (Da)
3.33
ALogP
5
HBA
2
HBD
85.4
PSA (Ų)
0.60
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 11 meas. best 8.1
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glycogen synthase kinase-3 beta CHEMBL262 | Ki | 8.1 | 8.1 | 7.9 | 1 |
| Rho-associated protein kinase 2 CHEMBL2973 | Ki | 7.7 | 7.7 | 19.9 | 1 |
| Dual specificity protein kinase CLK4 CHEMBL4203 | Ki | 7.6 | 7.6 | 25.1 | 1 |
| Cell division cycle 7-related protein kinase CHEMBL5443 | Ki | 7.5 | 7.48 | 31.6 | 2 |
| Cyclin-dependent kinase 2 CHEMBL301 | Ki | 7.1 | 7.1 | 79.4 | 1 |
| MAP kinase-interacting serine/threonine-protein kinase 2 CHEMBL4204 | Ki | 6.4 | 6.4 | 398.1 | 1 |
| cAMP-dependent protein kinase catalytic subunit alpha CHEMBL4101 | Ki | 6.2 | 6.2 | 631.0 | 1 |
| Mitogen-activated protein kinase kinase kinase kinase 4 CHEMBL6166 | Ki | 6.0 | 6.0 | 1000.0 | 1 |
| Homeodomain-interacting protein kinase 2 CHEMBL4576 | Ki | 5.7 | 5.7 | 1995.3 | 1 |
| Serine/threonine-protein kinase pim-1 CHEMBL2147 | Ki | 5.4 | 5.4 | 3981.1 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine